Relation of plasma brain natriuretic peptide levels in non-ST-elevation coronary disease and preserved systolic function to number of narrowed coronary arteries
| Autor: | V. Palazzuoli, Luigi Gennari, Paolo Calabria, Ranuccio Nuti, Ilaria Quatrini, Vincenzo De Paola, Maria Stella Campagna, Alberto Palazzuoli, Lucia Vecchiato |
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| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty medicine.drug_class Systole Heart Ventricles Coronary Angiography Severity of Illness Index Coronary artery disease Immunoenzyme Techniques Electrocardiography Risk Factors Internal medicine Natriuretic Peptide Brain medicine Natriuretic peptide Humans cardiovascular diseases Myocardial infarction Aged Retrospective Studies business.industry Unstable angina ST elevation Coronary Stenosis Middle Aged medicine.disease Brain natriuretic peptide Prognosis Myocardial Contraction Coronary arteries medicine.anatomical_structure Echocardiography Heart failure cardiovascular system Cardiology Female Cardiology and Cardiovascular Medicine business Biomarkers Follow-Up Studies |
| Popis: | Elevated plasma brain natriuretic peptide (BNP) levels have been described in patients with acute myocardial infarction and left ventricular dysfunction. The aim of the present study was to evaluate circulating BNP levels in patients with coronary artery disease without ST-segment elevation acute myocardial infarction and preserved systolic function and to evaluate the BNP levels in relation to the number of involved coronary vessels. We studied 88 patients with coronary artery disease: group 1 had stable angina, group 2 had unstable angina (UA), group 3 had non-Q-wave myocardial infarction (NSTEMI), and group 0 consisted of 15 healthy subjects. All recruited subjects underwent angiographic examination and echocardiographic evaluation. No patients had heart failure, previous myocardial infarction, or electrocardiographic ST elevation. A significant increase in BNP levels was observed in the UA and NSTEMI groups compared with the stable angina group (stable angina 31.3 pg/ml, UA 147.3 pg/ml, NSTEMI, 165.8 pg/ml, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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