The effect of vigorous running and cycling on serum COMP, lubricin, and femoral cartilage thickness: a pilot study
Autor: | Jonathan P. Moore, Matthew B. Fortes, Claire Griffith-Mcgeever, Harry M. Roberts, Jeanette M. Thom |
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Rok vydání: | 2016 |
Předmět: |
Adult
Cartilage Articular Male medicine.medical_specialty Adolescent Knee Joint Sports medicine Physiology Physical Exertion Pilot Projects Cartilage metabolism Cartilage Oligomeric Matrix Protein Condyle Running Young Adult 03 medical and health sciences 0302 clinical medicine Time trial Proteoglycan 4 Physiology (medical) Internal medicine medicine Humans Orthopedics and Sports Medicine Femur Glycoproteins 030203 arthritis & rheumatology Cartilage oligomeric matrix protein biology business.industry Public Health Environmental and Occupational Health Organ Size 030229 sport sciences General Medicine Middle Aged Bicycling biology.protein Cardiology Female Cycling business human activities |
Zdroj: | European Journal of Applied Physiology. 116:1467-1477 |
ISSN: | 1439-6327 1439-6319 |
Popis: | Our aim was to investigate lubricin, cartilage oligomeric matrix protein (COMP), and femoral cartilage deformation in response to different biomechanical loading of the knee joint (running vs cycling). Serum lubricin and COMP concentrations (enzyme-linked immunosorbent assay), and femoral cartilage thickness (suprapatellar transverse ultrasonography) were determined in 11 male runners (age: 40 ± 6 years; weight: 76 ± 8 kg) and 11 male cyclists (35 ± 12 years; 75 ± 5 kg) at baseline, immediately after, and 30 min after vigorous exercise (time trial: 10-km run or 25-km cycle). At baseline, lubricin (runners: 104.0 ± 19.8 ng/ml; cyclists: 119.1 ± 23.9 ng/ml) and COMP (runners: 804.1 ± 87.5 ng/ml; cyclists: 693.0 ± 84.7 ng/ml) did not significantly differ; however, vigorous exercise was accompanied by an increase in lubricin (cyclists: 39.4 %; p |
Databáze: | OpenAIRE |
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