The effect of vigorous running and cycling on serum COMP, lubricin, and femoral cartilage thickness: a pilot study

Autor: Jonathan P. Moore, Matthew B. Fortes, Claire Griffith-Mcgeever, Harry M. Roberts, Jeanette M. Thom
Rok vydání: 2016
Předmět:
Zdroj: European Journal of Applied Physiology. 116:1467-1477
ISSN: 1439-6327
1439-6319
Popis: Our aim was to investigate lubricin, cartilage oligomeric matrix protein (COMP), and femoral cartilage deformation in response to different biomechanical loading of the knee joint (running vs cycling). Serum lubricin and COMP concentrations (enzyme-linked immunosorbent assay), and femoral cartilage thickness (suprapatellar transverse ultrasonography) were determined in 11 male runners (age: 40 ± 6 years; weight: 76 ± 8 kg) and 11 male cyclists (35 ± 12 years; 75 ± 5 kg) at baseline, immediately after, and 30 min after vigorous exercise (time trial: 10-km run or 25-km cycle). At baseline, lubricin (runners: 104.0 ± 19.8 ng/ml; cyclists: 119.1 ± 23.9 ng/ml) and COMP (runners: 804.1 ± 87.5 ng/ml; cyclists: 693.0 ± 84.7 ng/ml) did not significantly differ; however, vigorous exercise was accompanied by an increase in lubricin (cyclists: 39.4 %; p
Databáze: OpenAIRE