Nutritional Supplements Used in Weight-reduction Programs Increase Intestinal Gas in Persons Who Malabsorb Lactose
| Autor: | Fabrizis L. Suarez, Michael D. Levitt, Luisa M. Zumarraga, Julie K. Furne |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
medicine.medical_specialty Diet Reducing medicine.medical_treatment Lactose Statistics Nonparametric chemistry.chemical_compound Lactose Intolerance Bloating Animal science Double-Blind Method medicine Animals Flatulence Humans Ingestion Lactase Food Formulated Meal Cross-Over Studies Nutrition and Dietetics Dose-Response Relationship Drug business.industry Middle Aged beta-Galactosidase Crossover study Abdominal Pain Surgery Diarrhea Milk Breath Tests chemistry Female Soybeans medicine.symptom business Food Science |
| Zdroj: | Journal of the American Dietetic Association. 101:1447-1452 |
| ISSN: | 0002-8223 |
| DOI: | 10.1016/s0002-8223(01)00349-2 |
| Popis: | Objective To determine if ingestion of 2 doses of milk-based dietary supplements produce gaseous symptoms in subjects who malabsorb lactose. Design Randomized, controlled, crossover trial. Subjects/setting Ten community-based subjects who malabsorb lactose. Intervention Ingestion of 2 standard servings of milk-based supplements (a powder reconstituted in fat-free milk or a ready-to-drink preparation) or low-lactose control preparations. Main outcome measures Frequency of flatus passage and subjective impression of bloating, flatulence, and abdominal discomfort. Statistical analysis Wilcoxon signed-rank test. Results The high lactose content (27g) of 2 servings of the powder-based supplement ingested without other food resulted in a marked increase in daily flatus passages from the basal level of 9.7±8.2 to 30±14 (mean ±SD), and a significant increase in the subjects' perception of gas. In contrast, the lower lactose content (18.4g) of 2 servings of a ready-to-drink supplement resulted in a flatus frequency of 17±10 (P=.14 vs baseline) and no significant increase in the perception of increased gas. Neither supplement resulted in a significant increase in bloating, abdominal pain, or diarrhea. The lactose content of the liquid supplement was reduced by 80% following overnight incubation with an over-the-counter lactase preparation. Applications/conclusions Persons who malabsorb lactose should be aware that sizable increases in rectal gas commonly occur when milk-based powders reconstituted in milk are used as meal replacements. In contrast, gas problems probably will be minor following ingestion of 2 doses of a ready-to-drink, milk-based supplement. The lactose content of these supplements can be markedly reduced by overnight incubation with over-the-counter lactase preparations, and this manipulation should be beneficial for subjects troubled by the increased gas caused by the consumption of lactose-containing supplements. J Am Diet Assoc. 2001;101:1447–1452 . |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect