Impact of attenuation correction and gated acquisition in SPECT myocardial perfusion imaging: results of the multicentre SPAG (SPECT Attenuation Correction vs Gated) study
| Autor: | Assuero Giorgetti, M. Rossi, Rita Bonini, Annadina Romeo, Francesco Bertagna, Alessia Gimelli, Annette Kusch, Paolo Marzullo, Giorgio Cannizzaro, Raffaele Giubbini, Irene D’Aragona Tagliavia, Pietro Bertolaccini, Mirta Casagranda, Giorgio Fagioli, Dario Genovesi |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Coronary angiography Gated SPECT Coronary Artery Disease Ct attenuation Single-photon emission computed tomography Body Mass Index Coronary artery disease Myocardial perfusion imaging Sex Factors Image Processing Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Aged Aged 80 and over medicine.diagnostic_test business.industry Myocardial Perfusion Imaging General Medicine Middle Aged medicine.disease Coronary Vessels Female Artifacts Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography Tomography X-Ray Computed business Nuclear medicine Body mass index Correction for attenuation |
| Zdroj: | European Journal of Nuclear Medicine and Molecular Imaging. 38:1890-1898 |
| ISSN: | 1619-7089 1619-7070 |
| DOI: | 10.1007/s00259-011-1855-4 |
| Popis: | In clinical myocardial single photon emission computed tomography (SPECT), attenuation artefacts may cause a loss of specificity in the identification of diseased vessels that can be corrected by means of gated SPECT (GSPECT) acquisition or CT attenuation correction (AC). The purpose of this multicentre study was to assess the impact of GSPECT and AC on the diagnostic performance of myocardial scintigraphy, according to patient’s sex, body mass index (BMI) and site of coronary artery disease (CAD). We studied a group of 104 patients who underwent coronary angiography within 1 month before or after the SPECT study. Patients with a BMI > 27 were considered “overweight”. Attenuation-corrected and standard GSPECT early images were randomly interpreted by three readers blinded to the clinical data. In the whole group, GSPECT and AC showed a diagnostic accuracy of 86.5% (sensitivity 82%, specificity 93%) and 77% (sensitivity 75.4%, specificity 81.4%), respectively (p |
| Databáze: | OpenAIRE |
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