A cytochemical profile of mucus-secreting, ciliated and subcolumnar basal cells of the human cerivical mucous membrane
| Autor: | J. M. Papadimitriou, R. A. Barter, P. R. Gould |
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| Rok vydání: | 1980 |
| Předmět: |
Adult
Cell type Histology Acid Phosphatase Cervix Uteri Biology Aminopeptidase Nucleotidase Thiamine pyrophosphatase Humans Tissue Distribution Molecular Biology Aged NADPH dehydrogenase Mucous Membrane Histocytochemistry Esterases NADPH Dehydrogenase Acid phosphatase NADH Dehydrogenase Cell Biology General Medicine Middle Aged Alkaline Phosphatase Mucus Molecular biology Enzymes Microscopy Electron Medical Laboratory Technology Biochemistry biology.protein Alkaline phosphatase Female Anatomy General Agricultural and Biological Sciences |
| Zdroj: | Histochemistry. 70:43-51 |
| ISSN: | 1432-119X 0301-5564 |
| DOI: | 10.1007/bf00508845 |
| Popis: | A range of enzymatic activities in cervical mucus-secreting, ciliated and subcolumnar basal cells were assessed using light and electron microscopic cytochemical techniques. Enzymes detected in all three cell types were those of the tricarboxylic acid cycle, pentose-phosphate and glycolytic pathways, other mitochondrial associated enzymes (NADH and NADPH dehydrogenase), acid phosphatase and non-specific esterase. Mucus-secreting and ciliated cells exhibited thiamine pyrophosphatase and 5' nucleotidase activities while leucine aminopeptidase was most convincingly demonstrated in mucus-secreting cells. Alkaline phosphatase, on the other hand, was detected only in mucus-secreting and subcolumnar basal cells. The profile of enzymatic activities in subcolumnar basal cells closely resembles that of mature lining cells and further supports the hypothesis that these cells differentiate into functioning columnar cells. |
| Databáze: | OpenAIRE |
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