IVF outcome in women with accidental contamination of follicular fluid with endometrioma content
| Autor: | Luigi Fedele, Alessio Paffoni, Laura Benaglia, Cristina Guarneri, Liliana Restelli, Edgardo Somigliana, Lucia Cardellicchio |
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| Rok vydání: | 2014 |
| Předmět: |
Infertility
Adult medicine.medical_specialty Pregnancy Rate Clinical pregnancy Endometriosis Oocyte Retrieval Fertilization in Vitro Pregnancy Surgical removal medicine Humans Ivf outcome Retrospective Studies Gynecology business.industry Obstetrics and Gynecology medicine.disease Follicular fluid Follicular Fluid Reproductive Medicine Accidental Female business Live birth Infertility Female Live Birth |
| Zdroj: | European journal of obstetrics, gynecology, and reproductive biology. 181 |
| ISSN: | 1872-7654 |
| Popis: | Objective To evaluate whether accidental contamination of follicular fluid with endometrioma content during oocytes retrieval affects IVF outcome. Study design We set up a retrospective review of women undergoing IVF in our infertility unit during a four years period. Cases were 19 women with ovarian endometriomas who had an accidental aspiration of the endometrioma content during oocyte retrieval. Controls (n = 38) were the two subsequent age-matched women with endometriomas who underwent an uncomplicated oocyte retrieval. The main outcome was to evaluate the clinical pregnancy rate in cases and in controls. Results Accidental aspiration of endometrioma content occurred in 19 out of 314 women (6.1%, 95%CI: 3.8–9.1%). The number of embryos and top quality embryos was significantly higher in exposed women (3.1 ± 2.0 versus 1.7 ± 1.2 and 1.9 ± 1.5 versus 1.1 ± 1.1, respectively) but the chances of pregnancy were lower. The adjusted RRs of clinical pregnancy and live birth were 0.63 (95%CI: 0.49–0.87, p = 0.005) and 0.60 (95%CI: 0.51–086, p = 0.003), respectively. Conclusion Accidental contamination of the follicular fluid with endometrioma content is an uncommon but possible event. This situation may affect IVF outcome but does not justify systematic surgical removal before the cycle. |
| Databáze: | OpenAIRE |
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