Predictors of early post-operative hypocalcemia after parathyroidectomy for secondary hyperparathyroidism
| Autor: | Sabra Aloui, Mouna Hamouda, N Ben Dhia, H. Skhiri, S El Mhamedi, Mezri Elmay |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Parathyroidectomy
Adult Male medicine.medical_specialty Adolescent endocrine system diseases medicine.medical_treatment lcsh:Medicine Gastroenterology Young Adult Postoperative Complications Risk Factors Internal medicine medicine Humans Young adult Aged Hyperparathyroidism Hypocalcemia business.industry lcsh:R Albumin General Medicine Odds ratio Stepwise regression Middle Aged medicine.disease Endocrinology Parathyroid Hormone Multivariate Analysis Alkaline phosphatase Secondary hyperparathyroidism Female Hyperparathyroidism Secondary business |
| Zdroj: | Saudi Journal of Kidney Diseases and Transplantation, Vol 24, Iss 6, Pp 1165-1169 (2013) |
| ISSN: | 1319-2442 |
| Popis: | We sought to identify predictors of development of early post-operative hypocalcemia after parathyroidectomy for secondary hyperparathyroidism. The patients were divided into two groups according to their serum calcium (Ca) levels within 24 hours of undergoing para-thyroidectomy: the hypocalcemia group (22 patients) with post-operative serum Ca levels of 2 mmol/L or less, and the normocalcemia group (48 patients), with post-operative serum Ca levels higher than 2 mmol/L. By using multivariate stepwise logistic regression analysis, high pre-operative serum Ca level had the strongest predictive value of development of early hypocalcemia with an adjusted odds ratio (aOR) of 3.01, followed by hypo-albuminemia (aOR = 2.72), younger age (aOR = 2.56), and high pre-operative alkaline phosphatase (ALP) levels (aOR = 2.28). We conclude that among patients with secondary hyperparathyroidism, age, levels of pre-operative serum Ca, ALP and albumin correlate positively with the development of early post-operative hypocalcemia. Patients with one of these factors should be monitored more closely in the early post-parathyroidectomy period. |
| Databáze: | OpenAIRE |
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