Motor Profile and Drug Treatment of Nursing Home Residents with Parkinson's Disease

Autor: Raymond T.C.M. Koopmans, Bastiaan R. Bloem, Marten Munneke, Nico J. Weerkamp, P.J.E. Poels, Gerrit Tissingh, Sytse U Zuidema
Přispěvatelé: Life Course Epidemiology (LCE)
Rok vydání: 2012
Předmět:
Male
Parkinson's disease
Movement disorders
Activities of daily living
Functional Neurogenomics Human Movement & Fatigue [DCN 2]
PROGRESSION
Disease
law.invention
CLINICAL CHARACTERISTICS
Quality of life
Randomized controlled trial
QUALITY-OF-LIFE
law
Activities of Daily Living
DCN MP - Plasticity and memory NCEBP 4 - Quality of hospital and integrated care
Medicine
POPULATION
Aged
80 and over
COMPLICATIONS
education.field_of_study
drug treatment
Parkinson Disease
Effective primary care and public health [NCEBP 7]
RANDOMIZED CONTROLLED-TRIAL
PREVALENCE
nursing home
Human Movement & Fatigue [DCN MP - Plasticity and memory NCEBP 10]
Female
medicine.symptom
medicine.drug
Levodopa
medicine.medical_specialty
DCN MP - Plasticity and memory
Quality of nursing and allied health care [NCEBP 6]
Population
SPES-SCOPA
Humans
Alzheimer Centre [NCEBP 11]
education
Aged
motor profile
Dyskinesias
business.industry
LEVODOPA
CARE
medicine.disease
Nursing Homes
Physical therapy
Geriatrics and Gerontology
Quality of hospital and integrated care [NCEBP 4]
business
SYDNEY MULTICENTER
Zdroj: Journal of the American Geriatrics Society, 60, 2277-82
Journal of the American Geriatrics Society, 60(12), 2277-2282. Wiley-Blackwell
Journal of the American Geriatrics Society, 60, 12, pp. 2277-82
ISSN: 0002-8614
DOI: 10.1111/jgs.12027
Popis: Objectives To examine the clinical characteristics, motor impairments, and drug treatments of nursing home residents with Parkinson's disease (PD).Design Cross-sectional study.Setting Nursing homes in the southeast of the Netherlands.Participants Nursing home residents with PD and a Mini-Mental State Examination score of 18 or greater seen by a physician with experience in movement disorders.Measurements Participant characteristics, motor function, and dopaminergic medications were assessed. The Short Parkinson's Evaluation Scale/SCales for Outcomes in Parkinson's disease (SPES-SCOPA) was used to assess motor impairments and disabilities.Results Seventy-three nursing home residents with PD (mean age 78.7; 45% male; mean disease duration 10.1 years; Hoehn and Yahr 4 (38%) and 5 (49%)) were included. Most residents were severely disabled, 49% being wheelchair bound. According to the SPES-SCOPA, 44% of residents were off (in a motor state in which they are slow and stiff) most of the time. Dyskinesias were encountered infrequently. Most residents were mainly treated with levodopa monotherapy, and daily doses varied widely (201,600 mg, mean 673 mg); 25% of residents were treated with less than 400 mg levodopa daily, and 8% received no levodopa at all. The movement disorders specialist considered 32 residents to be possibly undertreated.Conclusion These findings show that PD in nursing home residents is characterized by severe motor impairment and a high proportion of daily off time, which underscores the need for better management of PD in nursing homes, for example within specialized institutions or with periodic consultations by a movement disorders expert. J Am Geriatr Soc 60:2277-2282, 2012.
Databáze: OpenAIRE
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