The oil-rich alga Schizochytrium sp as a dietary source of docosahexaenoic acid improves shape discrimination learning associated with visual processing in a canine model of senescence
| Autor: | K.B. Hadley, N.W. Milgram, J. Bauer |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Senescence Aging Docosahexaenoic Acids Clinical Biochemistry Schizochytrium Biology Dinoprost Visual processing Discrimination Learning 03 medical and health sciences 0302 clinical medicine Dogs Dietary Fats Unsaturated Animals Humans Discrimination learning Food science Phospholipids chemistry.chemical_classification Working memory Cell Biology biology.organism_classification Disease Models Animal 030104 developmental biology Memory Short-Term Biochemistry chemistry Docosahexaenoic acid Memory consolidation 030217 neurology & neurosurgery Stramenopiles Polyunsaturated fatty acid |
| Zdroj: | Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA). |
| ISSN: | 0952-3278 |
| DOI: | 10.1016/j.plefa.2017.01.011 |
| Popis: | Whole cell Schizochytrium sp. is a rich source of omega-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) including docosahexaenoic acid (DHA), an important nutrient for brain health. Aged beagle dogs experienced on a visuospatial task of working memory, variable-delay delayed-non-matching-to-position were used to assess efficacy of DHA-rich microalgae based upon DHA wt% of total phospholipids and 8-iso-PGF2α concentrations in plasma, and performance on cognitive assessments of visual object discrimination, learning, and memory consolidation after 25 weeks on fortified diet. Improved DHA status (p |
| Databáze: | OpenAIRE |
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