In vitro, ex vivo and in vivo techniques to study neuronal migration in the developing cerebral cortex
Autor: | Anna Cariboni, Roberto Oleari, Valentina Andre, Antonella Lettieri, Roberta Azzarelli |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Migrating neuron Review Biology Migration assays Inhibitory postsynaptic potential lcsh:RC321-571 03 medical and health sciences 0302 clinical medicine In vivo Cortex (anatomy) medicine lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Migration Assay General Neuroscience In vitro 030104 developmental biology medicine.anatomical_structure Electroporation nervous system Cerebral cortex Excitatory postsynaptic potential Cortex Neuroscience 030217 neurology & neurosurgery Ex vivo |
Zdroj: | Brain Sciences, Vol 7, Iss 5, p 48 (2017) Brain Sciences |
Popis: | Neuronal migration is a fundamental biological process that underlies proper brain development and neuronal circuit formation. In the developing cerebral cortex, distinct neuronal populations, producing excitatory, inhibitory and modulatory neurotransmitters, are generated in different germinative areas and migrate along various routes to reach their final positions within the cortex. Different technical approaches and experimental models have been adopted to study the mechanisms regulating neuronal migration in the cortex. In this review, we will discuss the most common in vitro, ex vivo and in vivo techniques to visualize and study cortical neuronal migration. |
Databáze: | OpenAIRE |
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