Clinical Features and Surveillance of Very Late Hepatocellular Carcinoma Recurrence After Liver Transplantation
| Autor: | Hwi-Dong Cho, Jae Hyun Kwon, Gil-Chun Park, Shin Hwang, Chul-Soo Ahn, Sung-Gyu Lee, Gi-Won Song, Ki-Hun Kim, Su-Min Ha, Deok-Bog Moon, Tae-Yong Ha, Sang-Hyun Kang, Abdulwahab A Alshahrani, Dong-Hwan Jung |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Carcinoma Hepatocellular medicine.medical_treatment Liver transplantation Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine Late Recurrence medicine Carcinoma Humans 030212 general & internal medicine Neoplasm Metastasis Survival rate Aged Tumor marker Original Paper Transplantation Lung business.industry Liver Neoplasms General Medicine Middle Aged medicine.disease Liver Transplantation Survival Rate Treatment Outcome medicine.anatomical_structure Hepatocellular carcinoma Extrahepatic metastasis Female 030211 gastroenterology & hepatology Neoplasm Recurrence Local business |
| Zdroj: | Annals of Transplantation |
| ISSN: | 2329-0358 |
| DOI: | 10.12659/aot.910598 |
| Popis: | BACKGROUND This study aimed to assess patterns of hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) and to establish long-term surveillance protocols for late HCC recurrence. MATERIAL AND METHODS The 232 LT recipients experiencing subsequent HCC recurrence were categorized as Group 1, early recurrence (within 1 year of LT; n=117); Group 2, late recurrence (occurring in years 2-5; n=93); and Group 3, very late recurrence (after year 5; n=22). RESULTS Recurrence was detected by only elevated tumor marker levels in 11.1%, 30.1%, and 45.5% of patients in Groups 1, 2, and 3, respectively (p |
| Databáze: | OpenAIRE |
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