Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix
| Autor: | Heiner Nagursky, Federico Mandelli, Carlo Maiorana, Tiziano Testori, Matteo Deflorian, Raffaele Vinci, Pier Paolo Poli |
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| Přispěvatelé: | Maiorana, Carlo, Poli, Pier Paolo, Deflorian, Matteo, Testori, Tiziano, Mandelli, Federico, Nagursky, Heiner, Vinci, Raffaele |
| Rok vydání: | 2017 |
| Předmět: |
Histology
Tooth loss Dentistry Connective tissue Bone healing 03 medical and health sciences 0302 clinical medicine Bone cell Alveolar ridge Bone substitute Medicine Bone regeneration Socket preservation Bone substitutes business.industry Tooth lo Soft tissue 030206 dentistry Resorption medicine.anatomical_structure 030220 oncology & carcinogenesis Periodontics Oral Surgery business Research Article |
| Zdroj: | Journal of Periodontal & Implant Science |
| ISSN: | 2093-2278 |
| Popis: | Purpose The aim of the present study was to evaluate the healing of post-extraction sockets following alveolar ridge preservation clinically, radiologically, and histologically. Methods Overall, 7 extraction sockets in 7 patients were grafted with demineralised bovine bone mineral and covered with a porcine-derived non-crosslinked collagen matrix (CM). Soft tissue healing was clinically evaluated on the basis of a specific healing index. Horizontal and vertical ridge dimensional changes were assessed clinically and radiographically at baseline and 6 months after implant placement. For histological and histomorphometric analysis, bone biopsies were harvested from the augmented sites during implant surgery 6 months after the socket preservation procedure. Results Clinically, healing proceeded uneventfully in all the sockets. A trend towards reduced horizontal and vertical socket dimensions was observed from baseline to the final examination. The mean width and height of resorption were 1.21 mm (P=0.005) and 0.46 mm (P=0.004), respectively. Histologically, residual xenograft particles (31.97%±3.52%) were surrounded by either newly formed bone (16.02%±7.06%) or connective tissue (50.67%±8.42%) without fibrous encapsulation. The CM underwent a physiological substitution process in favour of well-vascularised collagen-rich connective tissue. Conclusions Socket preservation using demineralised bovine bone mineral in combination with CM provided stable dimensional changes of the alveolar ridge associated with good re-epithelialisation of the soft tissues during a 6-month healing period. Graphical Abstract |
| Databáze: | OpenAIRE |
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