Guess what: Chronic 13q14.3+/CD5−/CD23+lymphocytic leukemia in blood and t(11;14)(q13;q32)+/CD5+/CD23−mantle cell lymphoma in lymph nodes!

Autor:	Benvindo Justiça, José Manuel Cabeda, Sónia Fonseca, Luísa Pinto, Maria dos Anjos Teixeira, Paulo Brochado, Cidália Silva, Ana Helena Santos, Maria Luís Queirós, Margarida Lima, Áurea Canelhas, Alexandra Mota
Rok vydání:	2002
Předmět:	Male Pathology medicine.medical_specialty Histology Chronic lymphocytic leukemia Lymphoproliferative disorders Lymphoma Mantle-Cell CD5 Antigens Translocation Genetic Pathology and Forensic Medicine immune system diseases hemic and lymphatic diseases medicine Humans Aged Aged 80 and over Chromosomes Human Pair 14 Chromosomes Human Pair 13 Receptors IgE business.industry Chromosomes Human Pair 11 hemic and immune systems Cell Biology Flow Cytometry medicine.disease Leukemia Lymphocytic Chronic B-Cell Lymphoma Leukemia medicine.anatomical_structure Mantle cell lymphoma Lymph Nodes Lymph Bone marrow CD5 business
Zdroj:	Cytometry Part B: Clinical Cytometry. :41-44
ISSN:	1552-4949
Popis:	We report a case of a patient with two B-cell lymphoproliferative disorders: CD5(-)/CD23(+) B-cell chronic lymphocytic leukemia and CD5(+)/CD23(-) mantle cell lymphoma. These disorders were diagnosed simultaneously based on flow cytometry, immunohistochemistry, fluorescence in situ hybridization, and polymerase chain reaction-based molecular studies. The B-cell lymphocytic leukemia clone predominated in the blood and bone marrow, whereas the mantle cell clone predominated in lymph nodes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7999f6cdb633072be48c7bf9eefabfb1 https://doi.org/10.1002/cyto.b.10005 Zobrazit plný text záznamu