[Adherence to Oral Antihyperglycemic Agents (Dipeptidyl Peptidase-4 Inhibitors and Biguanides) and Its Associated Factors in Patients with Type 2 Diabetes]
| Autor: | Shigeru Tokita, Kotoba Okuyama, Takekazu Kubo, Miwako Kamei, Ai Hayashi |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty media_common.quotation_subject Biguanides Pharmaceutical Science Administration Oral Dipeptidyl peptidase-4 inhibitor Type 2 diabetes Anxiety Medication Adherence Young Adult Internal medicine medicine Humans Hypoglycemic Agents Dipeptidyl peptidase-4 media_common Aged Pharmacology Dipeptidyl-Peptidase IV Inhibitors business.industry Type 2 Diabetes Mellitus Middle Aged medicine.disease Regimen Feeling Diabetes Mellitus Type 2 Pill Female medicine.symptom business medicine.drug |
| Zdroj: | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 139(12) |
| ISSN: | 1347-5231 |
| Popis: | To investigate medication adherence to oral antihyperglycemic agents and its associated factors in Japanese type 2 diabetic patients, a questionnaire survey was conducted in 983 adult patients receiving once-daily (QD) or twice-daily (BID) dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitor) or BID biguanides (BG) as monotherapy at 502 pharmacies in Japan. The percentage of patients with good adherence (the proportion of days in which patients took all pills as prescribed in the past 7 days ≥80%) was high (≥90%) in any dosing regimen with no significant difference among the groups. The following factors were identified as associating with good adherence: the longer duration of type 2 diabetes (≥1 year) (p=0.002), "Feeling your disease gets worse if you don't take medications" (p=0.031), "Not forgetting to bring along your medicine when you leave home" (p=0.007), "Feeling anxiety on taking medications for long period of time" (p=0.042), "Neither feeling nor not feeling anxiety on taking medications for a long period of time" (p=0.004), "Never run out of your medicine because you get a refill on time" (p=0.035), and the lower MMAS-4 score (p |
| Databáze: | OpenAIRE |
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