Effects of Dynamic and Static Loads on the Concentration of Sodium and Potassium in Murine Skeletal Muscles
| Autor: | A. N. Zakharova, Kseniya Milovanova, Leonid V. Kapilevich, T. A. Kironenko, D A Fedorov, Svetlana V. Sidorenko, E. Yu. Dyakova, N S Orlov |
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| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Potassium Sodium chemistry.chemical_element Physical exercise General Biochemistry Genetics and Molecular Biology Weight-Bearing Mice 03 medical and health sciences 0302 clinical medicine Muscle Stretching Exercises Physical Conditioning Animal Myokine Animals Muscle Skeletal Swimming Ions Chemistry General Medicine Mice Inbred C57BL 030104 developmental biology Biophysics Functional activity 030217 neurology & neurosurgery Intracellular |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 169:1-4 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | The effects of dynamic and static load on the intracellular concentrations of sodium [Formula: see text] and potassium (K+i) in m. soleus and m. biceps, respectively, were studied in mice. Both dynamic (swimming for 60 min) and static (hanging on the grid for 40 min) load led to a 2-fold increase in [Formula: see text] level, a decrease in K+i concentration by 25-35%, and 3-4-fold increase in the [Formula: see text] ratio. These effects of dynamic and static loads on the studied parameters remained unchanged in mice subjected to regular physical exercise (swimming or hanging on the grid for 1 h a day over 4 weeks). Our results suggest that dissipation of sodium and potassium transmembrane gradients during physical exercise can be considered as a factor of regulation of functional activity of skeletal muscles, which includes changes in transcription and translation of myokines observed previously. |
| Databáze: | OpenAIRE |
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