Effect of time of day on walking capacity and self-reported fatigue in persons with multiple sclerosis: a multi-center trial
| Autor: | Francois Bethoux, Ulrik Dalgas, Carme Santoyo, Claude Vaney, Benoit Gebara, Kathy Knuts, B. Maertens de Noordhout, Peter Feys, V. de Groot, Domien Gijbels, Anders Romberg |
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| Přispěvatelé: | Rehabilitation medicine, EMGO - Musculoskeletal health, NCA - Multiple Sclerosis and Other Neuroinflammatory Diseases, MOVE Research Institute |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Multiple Sclerosis Time Factors Evening Walking Disability Evaluation Physical medicine and rehabilitation Time of day medicine Humans Increased fatigue Fatigue Aged Morning Expanded Disability Status Scale business.industry Multiple sclerosis Middle Aged medicine.disease Neurology Walk test Ambulatory Physical therapy Female Self Report Neurology (clinical) business |
| Zdroj: | Multiple Sclerosis, 18(3), 351-375. SAGE Publications Ltd Feys, P, Gijbels, D, Romberg, A, Santoyo, C, Gebara, B, Maertens de Noordhout, B, Knuts, K, Bethoux, F, de Groot, V, Vaney, C & Dalgas, U 2012, ' Effect of time of day on walking capacity and self-reported fatigue in persons with multiple sclerosis : a multi-center trial ', Multiple Sclerosis, vol. 18, no. 3, pp. 351-7 . https://doi.org/10.1177/1352458511419881 Feys, P, Gijbels, D, Romberg, A, Santoyo, C, Gebara, B, de Maertens, N B, Knuts, K, Bethoux, F, de Groot, V, Vaney, C & Dalgas, U 2012, ' Effect of time of day on walking capacity and self-reported fatigue in persons with multiple sclerosis: a multi-center trial. ', Multiple Sclerosis, vol. 18, no. 3, pp. 351-375 . https://doi.org/10.1177/1352458511419881 |
| ISSN: | 1352-4585 |
| Popis: | Background: Many persons with multiple sclerosis (PwMS) report increased fatigue in the afternoon and evening compared with the morning. It is commonly accepted that physical capacity also decreases as time of day progresses, potentially influencing the outcomes of testing. Objective: The objective of this article was to determine whether self-reported fatigue level and walking capacity are influenced by time of day in PwMS. Methods: A total of 102 PwMS from 8 centers in 5 countries, with a diverse level of ambulatory dysfunction (Expanded Disability Status Scale [EDSS] Results: Subgroups had different degree of ambulatory dysfunction ( p < 0.001) but reported similar fatigue levels. Although RFD scores were affected by time of day with significant differences between morning and noon/afternoon ( p < 0.0001), no changes in walking capacity were found in any subgroup. Additional analyses on subgroups distinguished by diurnal change in self-reported fatigue failed to reveal analogous changes in walking capacity. Conclusions: Testing of walking capacity is unaffected by time of day, despite changes in subjective fatigue. |
| Databáze: | OpenAIRE |
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