The Structural Biology Knowledgebase: a portal to protein structures, sequences, functions, and methods
| Autor: | Matthew D. Zimmerman, Paul D. Adams, Konstantin Arnold, Kouranov Andrei Y, Yi Ping Tao, Judith Flippen-Andersen, John D. Westbrook, David Micallef, Wladek Minor, William A. McLaughlin, Margaret Gabanyi, Raship Shah, Torsten Schwede, Lorenza Bordoli, Lester G. Carter, Juergen Haas, Lida Gifford, Helen M. Berman |
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| Rok vydání: | 2011 |
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Molecular Proteomics Protein structure database Protein Conformation Knowledge Bases Molecular Sequence Data Structural genomics Protein Data Bank (RCSB PDB) Biology Online Systems Biochemistry Article User-Computer Interface 03 medical and health sciences Structural Biology Protein production Genetics Theoretical models Amino Acid Sequence Databases Protein 030304 developmental biology Structural databases 0303 health sciences Protein 030302 biochemistry & molecular biology Proteins Full text search General Medicine computer.file_format Protein Data Bank Data science Structural biology Database Management Systems Web resource computer Protein Structure Initiative |
| Zdroj: | Journal of Structural and Functional Genomics |
| ISSN: | 1570-0267 1345-711X |
| Popis: | The Protein Structure Initiative's Structural Biology Knowledgebase (SBKB, URL: http://sbkb.org ) is an open web resource designed to turn the products of the structural genomics and structural biology efforts into knowledge that can be used by the biological community to understand living systems and disease. Here we will present examples on how to use the SBKB to enable biological research. For example, a protein sequence or Protein Data Bank (PDB) structure ID search will provide a list of related protein structures in the PDB, associated biological descriptions (annotations), homology models, structural genomics protein target status, experimental protocols, and the ability to order available DNA clones from the PSI:Biology-Materials Repository. A text search will find publication and technology reports resulting from the PSI's high-throughput research efforts. Web tools that aid in research, including a system that accepts protein structure requests from the community, will also be described. Created in collaboration with the Nature Publishing Group, the Structural Biology Knowledgebase monthly update also provides a research library, editorials about new research advances, news, and an events calendar to present a broader view of structural genomics and structural biology. |
| Databáze: | OpenAIRE |
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