Early Complications Related to the Transplanted Kidney After Simultaneous Pancreas and Kidney Transplantation
| Autor: | S. Frunze, K. Madej, Tomasz Jakimowicz, Magdalena Durlik, Zbigniew Gałązka, Sławomir Nazarewski, Jacek Szmidt, Leszek Pączek, Tadeusz Grochowiecki |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Graft Rejection Male medicine.medical_specialty medicine.medical_treatment Diabetic nephropathy Young Adult Postoperative Complications Diabetes mellitus medicine Humans Kidney transplantation Acute tubular necrosis Retrospective Studies Transplantation Kidney business.industry Graft Survival Thrombosis Middle Aged medicine.disease Kidney Transplantation Nephrectomy Surgery Diabetes Mellitus Type 1 medicine.anatomical_structure Mycoses Kidney Failure Chronic Female Kidney Cortex Necrosis Pancreas Transplantation business Complication |
| Zdroj: | Transplantation Proceedings. 46:2815-2817 |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2014.08.011 |
| Popis: | Objective Simultaneous pancreas and kidney transplantation (SPKTx) is the most often performed multiorgan transplantation. The main source of complication is transplanted pancreas; as a result, early complications related to kidney transplant are rarely assessed. The aim of this study was to evaluate prevalence, types, and severity of postoperative complications due to kidney graft among the simultaneous pancreas and kidney recipients. Methods Complications related to transplanted kidney among 112 SPKTx recipients were analyzed. The indication for SPKTx was end-stage diabetic nephropathy due to long-lasting diabetes type 1. The cumulative survival rates for kidney graft function and cumulative freedom from complication on days 60 and 90 after transplantation were assessed. Severity of complications was classified according to the modified Dindo-Clavien scale. Results The 12-month cumulative survival rate for kidney graft was 0.91. Cumulative freedom from complication on the 60th day after transplantation was 0.84. The rates for II, IIIA, IIIB, IVA, and IVB severity grades were: 34.9%, 4.3%, 26.1%, 26.1%, and 8.6%, respectively. Acute tubular necrosis and rejection were the most frequent (43.4%) cause of complication. The most frequent reasons for graft nephrectomy were infections (2/7; 28.6%) and vascular thrombosis due to atherosclerosis of recipient iliac arteries (2/7; 28.6%). The most severe (IVB) complications were caused by fungal infection. Conclusion Rate and severity of complications due to renal graft after SPKTx was low; however, to prevent the most serious ones reduction of fungal infection was necessary. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect