Unpacking the intricacies of Rickettsia-vector interactions
| Autor: | Kevin R Macaluso, Hanna J. Laukaitis |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Genetics Rickettsia species biology 030231 tropical medicine Arthropod Vectors Virulence Successful transmission Tick bacterial infections and mycoses biology.organism_classification Article 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Infectious Diseases Rickettsia Host-Pathogen Interactions Animals Parasitology Vector (molecular biology) |
| Zdroj: | Trends Parasitol |
| ISSN: | 1471-5007 |
| Popis: | Although Rickettsia species are molecularly detected among a wide range of arthropods, vector competence becomes an imperative aspect of understanding the eco-epidemiology of these vector-borne diseases. The synergy between vector homeostasis and rickettsial invasion, replication, and release initiated within hours (insects) and days (ticks) permits successful transmission of rickettsiae. Uncovering the molecular interplay between rickettsiae and their vectors necessitates examining the multi-faceted nature of rickettsial virulence and vector infection tolerance. Here, we highlight the biological differences between tick- and insect-borne rickettsiae and the factors facilitating the incidence of rickettsioses. Untangling the complex relationship between rickettsial genetics, vector biology, and microbial interactions is crucial in understanding the intricate association between rickettsiae and their vectors. |
| Databáze: | OpenAIRE |
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