Etiology of Invasive Bacterial Infections in Immunocompetent Children in Korea (2006–2010): a Retrospective Multicenter Study
| Autor: | Young Jin Hong, Young Min Ahn, Young Youn Choi, Kwang Nam Kim, Jin Han Kang, Dae Sun Jo, Yun Kyung Kim, Hoan Jong Lee, Kun Song Lee, Kyuyol Rhie, Eun Young Cho, Byung Wook Eun, Sung Ho Cha, Sung Hee Oh, Yae Jean Kim, Sang Hyuk Ma, Nam Hee Kim, Taekjin Lee, Jong Hyun Kim, Dong Soo Kim, Young Mi Kim, Hwang Min Kim, Su Eun Park, Chi Eun Oh, Chun Soo Kim, Eun Hwa Choi, Jina Lee |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Staphylococcus aureus medicine.medical_specialty Epidemiology medicine.disease_cause Streptococcus agalactiae Haemophilus influenzae Hospitals University Immunocompromised Host 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine Correspondence Republic of Korea Streptococcus pneumoniae Escherichia coli Humans Medicine 030212 general & internal medicine Retrospective Studies business.industry Infant Bacterial Infections General Medicine Infectious Diseases Microbiology & Parasitology medicine.disease Pneumonia Child Preschool Bacteremia Etiology Female Original Article business Meningitis |
| Zdroj: | Journal of Korean Medical Science |
| ISSN: | 1598-6357 1011-8934 |
| DOI: | 10.3346/jkms.2018.33.e45 |
| Popis: | Background Invasive bacterial infections in apparently immunocompetent children were retrospectively analyzed to figure causative bacterial organisms in Korea. Methods A total of 947 cases from 25 university hospitals were identified from 2006 to 2010 as a continuance of a previous 10-year period study from 1996 to 2005. Results Escherichia coli (41.3%), Streptococcus agalactiae (27.7%), and Staphylococcus aureus (27.1%) were the most common pathogens in infants < 3 months of age. S. agalactiae was the most prevalent cause of meningitis and pneumonia and E. coli was the major cause of bacteremia without localizing signs in this group. In children 3 to 59 months of age, Streptococcus pneumoniae (54.2%), S. aureus (20.5%), and Salmonella spp. (14.4%) were the most common pathogens. S. pneumoniae was the leading cause of pneumonia (86.0%), meningitis (65.0%), and bacteremia without localizing signs (49.0%) in this group. In children ≥ 5 years of age, S. aureus (62.8%) was the predominant pathogen, followed by Salmonella species (12.4%) and S. pneumoniae (11.5%). Salmonella species (43.0%) was the most common cause of bacteremia without localizing signs in this group. The relative proportion of S. aureus increased significantly over the 15-year period (1996–2010) in children ≥ 3 months of age (P < 0.001), while that of Haemophilus influenzae decreased significantly in both < 3 months of age group (P = 0.036) and ≥ 3 months of age groups (P < 0.001). Conclusion S. agalactiae, E. coli, S. pneumoniae, and S. aureus are common etiologic agents of invasive bacterial infections in Korean children. Graphical Abstract |
| Databáze: | OpenAIRE |
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