Barriers and Facilitators of PrEP Adherence for Young Men and Transgender Women of Color

Autor: José A. Bauermeister, Danielle Petsis, Helen C. Koenig, Linden Lalley-Chareczko, Meghan Swyryn, Nadia Dowshen, Judy A. Shea, Joshua Franklin, Robert E. Gross, Sarah M. Wood
Rok vydání: 2019
Předmět:
Male
Health Knowledge
Attitudes
Practice
medicine.medical_specialty
Social Psychology
Anti-HIV Agents
Social Stigma
HIV Infections
Pharmacy
Hiv risk
Transgender Persons
Health Services Accessibility
Article
Transgender women
Medication Adherence
Cohort Studies
Interviews as Topic
Sexual and Gender Minorities
Young Adult
03 medical and health sciences
Social support
Pre-exposure prophylaxis
Risk-Taking
0302 clinical medicine
Humans
Medicine
030212 general & internal medicine
Homosexuality
Male
Tenofovir
Qualitative Research
Philadelphia
030505 public health
business.industry
Public health
Stressor
Public Health
Environmental and Occupational Health
Social Support
Hispanic or Latino
Black or African American
Health psychology
Infectious Diseases
Family medicine
Female
Pre-Exposure Prophylaxis
0305 other medical science
business
Zdroj: AIDS Behav
ISSN: 1573-3254
1090-7165
Popis: We aimed to discover barriers and facilitators of HIV pre-exposure prophylaxis (PrEP) adherence in young men and transgender women of color who have sex with men (YMSM/TW). Short-term and sustained adherence were measured by urine tenofovir concentration and pharmacy refills, respectively. Optimal adherence was defined as having both urine tenofovir concentration consistent with dose ingestion within 48 hours and pharmacy refills consistent with ≥4 doses per week use. Participants completed semi-structured interviews exploring adherence barriers and facilitators. Participants (n=31) were primarily African-American (68%), mean age 22 years (SD: 1.8), and 48% had optimal adherence. Adherence barriers included stigma, health systems inaccessibility, side effects, competing stressors, and low HIV risk perception. Facilitators included social support, health system accessibility, reminders/routines, high HIV risk perception, and personal agency. Our findings identify targets for intervention to improve PrEP adherence in these populations, including augmenting health activation and improving accuracy of HIV risk perception.
Databáze: OpenAIRE
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