A portable device for cancer margin assessment using a pH sensitive optical fibre probe
| Autor: | David F. Callen, Erik P. Schartner, Malcolm S. Purdey, Tanya M. Monro, P. Grantley Gill, Matthew R. Henderson |
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| Přispěvatelé: | Schartner, Erik P, Henderson, Matthew R, Purdey, Malcolm, Monro, Tanya M, Gill, P Grantley, Callen, David F, 25th International Conference on Optical Fibre Sensors (OFS) Jeju, South Korea 24-28 April 2017 |
| Rok vydání: | 2017 |
| Předmět: |
Materials science
Optical fiber Fluorophore Healthy tissue 01 natural sciences law.invention 010309 optics 03 medical and health sciences chemistry.chemical_compound breast cancer 0302 clinical medicine Optics law Margin (machine learning) 0103 physical sciences melanoma Spectrometer pH business.industry optical fibre sensors chemistry 030220 oncology & carcinogenesis oncology fluorescence business Biomedical engineering |
| Zdroj: | SPIE Proceedings. |
| ISSN: | 0277-786X |
| Popis: | We report the development of an optical fibre probe which could find use as an aid for margin detection during surgery. A fluorophore doped polymer is coated on an optical fibre tip, allowing for pH values of unknown tissue to be measured and compared to healthy tissue, to discriminate between healthy and cancerous tissue. This probe is integrated within a portable system, requiring no alignment or access to specialised vibration damped optical tables. A miniature spectrometer allows for measurements to be performed on-site, opening up the potential for use of these probes within the operating theatre for in-vivo measurements. Refereed/Peer-reviewed |
| Databáze: | OpenAIRE |
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