Does Vaginal Cuff Creation and Avoidance of a Uterine Manipulator Improve the Prognosis of Total Laparoscopic Radical Hysterectomy for Early Cervical Cancer? A Retrospective Multicenter Study

Autor: Eiji Kondo, Kenta Yoshida, Michiko Kubo-Kaneda, Masafumi Nii, Kota Okamoto, Shoichi Magawa, Ryo Nimua, Asumi Okumura, Toshiharu Okugawa, Takaharu Yamawaki, Kenji Nagao, Kouichi Yoshimura, Naoki Watashige, Kenji Yanoh, Tomoaki Ikeda
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Cancers; Volume 14; Issue 18; Pages: 4389
ISSN: 2072-6694
DOI: 10.3390/cancers14184389
Popis: Our goal was to compare the treatment outcomes of open-abdominal radical hysterectomy (O-RH) and total laparoscopic hysterectomy (TLRH) with vaginal cuff creation and without using a uterine manipulator in stage IB1-B2 (tumor size < 4 cm) cervical cancer cases. In this retrospective multicenter analysis, 94 cervical cancer stage IB1-B2 patients who underwent O-RH or TLRH in six hospitals in Japan between September 2016 and July 2020 were included; 36 patients underwent TLRH. Propensity score matching was performed because the tumor diameter was large, and positive cases of lymph node metastases were included in the O-RH group due to selection bias. The primary endpoint was progression-free survival (PFS) and recurrence sites of TLRH and O-RH. PFS and OS (overall survival) were not significant in both the TLRH (n = 27) and O-RH (n = 27) groups; none required conversion to laparotomy. The maximum tumor size was
Databáze: OpenAIRE
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