A toolbox for tuberculosis (TB) diagnosis: an Indian multicentric study (2006-2008). Evaluation of QuantiFERON-TB gold in tube for TB diagnosis
| Autor: | Amit Singh, Subbalaxmi V. S. Malladi, Pratibha Sharma, Archana Sodha, Balambal Raman, Sarman Singh, Satheesh K. Thangaraj, Christophe Longuet, Alaka Deshpande, Enrico Girardi, Kiran Katoch, Vemu Lakshmi, Deepali Mukerjee, Manoj Kumar, Camilla Rodrigues, Alamelu Raja, Vishwa Mohan Katoch, Marc Leportier, Rajeshwar Dayal, Nirmal Kumar Ganguly, Delia Goletti, Deepthi Nair, Basirudeen Syed Ahamed Kabeer, Guy Vernet, Philippe H. Lagrange, Beenu Joshi |
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| Přispěvatelé: | Service de microbiologie [Saint-Louis], Université Paris Diderot - Paris 7 (UPD7)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), National Institute for Infectious Diseases 'Lazzaro Spallanzani' IRCCS, National Institute for Infectious Diseases 'Lazzaro Spallanzani', ACEEE, The Institute of Doctors Engineers and Scientists - IDES, Fondation Mérieux, Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP) |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Microbiological Techniques medicine.medical_specialty Tuberculosis [SDV]Life Sciences [q-bio] lcsh:Medicine Tuberculin HIV Infections QuantiFERON Mycobacterium Mycobacterium tuberculosis 03 medical and health sciences Young Adult 0302 clinical medicine Tuberculosis diagnosis Latent Tuberculosis Internal medicine medicine Humans 030212 general & internal medicine lcsh:Science Prospective cohort study 0303 health sciences Multidisciplinary Latent tuberculosis biology 030306 microbiology business.industry Tuberculin Test lcsh:R Middle Aged medicine.disease biology.organism_classification bacterial infections and mycoses 3. Good health Immunology Sputum lcsh:Q Female medicine.symptom business Interferon-gamma Release Tests Research Article |
| Zdroj: | PLoS ONE PLoS ONE, Public Library of Science, 2013, 8 (9), pp.e73579. ⟨10.1371/journal.pone.0073579⟩ PLoS ONE, Vol 8, Iss 9, p e73579 (2013) |
| ISSN: | 1932-6203 |
| Popis: | International audience; BACKGROUND: The aim of this multicentric prospective study in India was to assess the performance of the QuantiFERON TB-Gold in tube (QFT-GIT), Tuberculin Skin Test (TST) and microbiological results as additional tools for diagnosing active tuberculosis (TB) and latent infection (LTBI) according to Human Immunodeficiency Virus (HIV) status. METHODS: Individuals with and without active TB and HIV infection were enrolled between 2006-2008. QFT-GIT and TST results were analyzed per se and in combination with microbiological data. RESULTS: Among the 276 individuals (96 active pulmonary TB and 180 no active TB) tested by QFT-GIT, 18 indeterminate results (6.5%) were found, more significantly numerous in the HIV-infected (15/92; 16.3%) than the HIV-uninfected (3/184; 1.6%)(p |
| Databáze: | OpenAIRE |
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