Corticosteroid injection treatment for dactylitis in psoriatic arthritis
Autor: | Salvatore D'Angelo, Ennio Lubrano, Antonio Carriero, V. Picerno, Angela Padula |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
corticosteroid dactylitis medicine.drug_class Therapeutic treatment Diseases of the musculoskeletal system Review urologic and male genital diseases law.invention Dactylitis Psoriatic arthritis Rheumatology Randomized controlled trial law medicine Clinical endpoint Orthopedics and Sports Medicine psoriatic arthritis therapy Tenosynovitis treatment business.industry ultrasound Intra-articular Treatment Options in the Management of Joint Disorders medicine.disease Dermatology tenosynovitis RC925-935 injection Current practice Corticosteroid business |
Zdroj: | Therapeutic Advances in Musculoskeletal Disease Therapeutic Advances in Musculoskeletal Disease, Vol 13 (2021) |
ISSN: | 1759-7218 1759-720X |
Popis: | Dactylitis – a hallmark clinical feature of psoriatic arthritis (PsA) – that occurs in 30–50% of PsA patients, is a marker of disease severity for PsA progression, an independent predictor of cardiovascular morbidity and impairs the motor functions of PsA patients. There is a paucity of evidence for the treatment due to the absence of randomized controlled trials assessing dactylitis as a primary endpoint and current practice arises from the analysis of dactylitis as a secondary outcome. Corticosteroid (CS) injections for dactylitis in PsA patients are a therapeutic treatment option for patients with isolated dactylitis or for patients with flares in tendon sheaths, despite stable and effective systemic treatment. The aim of this narrative review is to briefly illustrate the clinical aspects of dactylitis in PsA, the imaging and clinimetric tools used to diagnose and monitor dactylitis, the current treatment strategies and principally to provide a comprehensive picture of the clinical efficacy and safety with ultrasound-guide and blind techniques of CS injections for dactylitis in PsA patients. |
Databáze: | OpenAIRE |
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