Diagnostic and Prognostic Value of Cardiac Magnetic Resonance Imaging in Assessing Myocardial Viability

Autor: Hema Korlakunta, Raymond Y. Kwong
Rok vydání: 2008
Předmět:
Adult
Gadolinium DTPA
Male
medicine.medical_specialty
Cell Survival
medicine.medical_treatment
Myocardial Infarction
Myocardial Ischemia
Magnetic Resonance Imaging
Cine
Coronary Disease
Myocardial Reperfusion
Revascularization
Sensitivity and Specificity
Coronary artery disease
Cardiac magnetic resonance imaging
Internal medicine
Image Processing
Computer-Assisted
medicine
Humans
Radiology
Nuclear Medicine and imaging
cardiovascular diseases
Aged
Tissue Survival
Tomography
Emission-Computed
Single-Photon
Ventricular Remodeling
medicine.diagnostic_test
business.industry
Myocardium
Magnetic resonance imaging
Perioperative
Middle Aged
Image Enhancement
Prognosis
medicine.disease
Magnetic Resonance Imaging
Positron-Emission Tomography
Cardiac chamber
cardiovascular system
Cardiology
Female
Myocardial infarction diagnosis
business
Perfusion
Zdroj: Topics in Magnetic Resonance Imaging. 19:15-24
ISSN: 0899-3459
DOI: 10.1097/rmr.0b013e31817d550c
Popis: Assessment of viability is pivotal to the prognosis of patients with chronic coronary artery disease (CAD) and left ventricular dysfunction. Patients with viable myocardium have a better prognosis with revascularization; however, patients with nonviable myocardium have worse outcomes with higher perioperative morbidity and mortality subsequent to revascularization. Cardiac magnetic resonance (CMR) imaging not only is the current reference standard technique in measuring cardiac chamber size and function and myocardial mass and volume but also provides spatially registered 2- or 3-dimensional data sets in myocardial perfusion and myocardial contrast enhancement in the same imaging session. Late gadolinium enhancement by CMR is the best current technique in discriminating myocardial scar versus viable myocardium. An extensive body of preclinical evidence has validated the detection and characterization of the morphology of infarcted tissue. In clinical studies, infarct characteristics by CMR has demonstrated a strong clinical utility in the prediction of left ventricular functional recovery and patient prognosis. In this paper, we aim to review the current CMR techniques in characterizing the spectrum of myocardial changes because of CAD, in the prediction of myocardial viability, and the current evidence of CMR's role in patient prognosis. In addition, we will also review the current literature comparing the clinical utility of CMR with other established imaging modalities in the assessment of CAD.
Databáze: OpenAIRE
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