Commentary: Roles for Pathologists in a High-throughput Image Analysis Team
Autor: | Famke Aeffner, Dan Rudmann, Brad Bolon, Kristin Wilson, Charles R. Mahrt, Suzanne Kanaly, G. David Young, Elaine Charles |
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Rok vydání: | 2016 |
Předmět: |
040301 veterinary sciences
MEDLINE Toxicology Pathology and Forensic Medicine 0403 veterinary science 03 medical and health sciences Annotation 0302 clinical medicine Software Image Interpretation Computer-Assisted Medicine Humans Set (psychology) Molecular Biology Throughput (business) Pathology Clinical business.industry Digital pathology 04 agricultural and veterinary sciences Cell Biology Data science Analytical algorithm Pathologists 030220 oncology & carcinogenesis Digital image analysis business |
Zdroj: | Toxicologic pathology. 44(6) |
ISSN: | 1533-1601 |
Popis: | Historically, pathologists perform manual evaluation of H&E- or immunohistochemically-stained slides, which can be subjective, inconsistent, and, at best, semiquantitative. As the complexity of staining and demand for increased precision of manual evaluation increase, the pathologist’s assessment will include automated analyses (i.e., “digital pathology”) to increase the accuracy, efficiency, and speed of diagnosis and hypothesis testing and as an important biomedical research and diagnostic tool. This commentary introduces the many roles for pathologists in designing and conducting high-throughput digital image analysis. Pathology review is central to the entire course of a digital pathology study, including experimental design, sample quality verification, specimen annotation, analytical algorithm development, and report preparation. The pathologist performs these roles by reviewing work undertaken by technicians and scientists with training and expertise in image analysis instruments and software. These roles require regular, face-to-face interactions between team members and the lead pathologist. Traditional pathology training is suitable preparation for entry-level participation on image analysis teams. The future of pathology is very exciting, with the expanding utilization of digital image analysis set to expand pathology roles in research and drug development with increasing and new career opportunities for pathologists. |
Databáze: | OpenAIRE |
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