Gastric emptying in patients on renal replacement therapy

Autor:	Sukru Sindel, Tamer Atasever, Şevki Sert, Zeynep Arzu Yegin, Nilüfer Yildirim Poyraz, Galip Guz, Ibrahim Dogan, Oktay Bagdatoglu, Musa Bali
Rok vydání:	2004
Předmět:	Nephrology Adult Male medicine.medical_specialty Time Factors medicine.medical_treatment Nutritional Status Critical Care and Intensive Care Medicine urologic and male genital diseases Gastroenterology Risk Assessment Statistics Nonparametric Peritoneal dialysis Blood Urea Nitrogen Body Mass Index Cohort Studies Renal Dialysis Internal medicine medicine Humans Renal replacement therapy Blood urea nitrogen Probability Kidney Gastric emptying Anthropometry business.industry General Medicine Middle Aged Prognosis Kidney Transplantation Surgery Transplantation medicine.anatomical_structure Gastric Emptying Kidney Failure Chronic Female Hemodialysis business Peritoneal Dialysis Blood Chemical Analysis
Zdroj:	Renal failure. 26(6)
ISSN:	0886-022X
Popis:	In addition to gastrointestinal tract symptoms such as nausea, vomiting, and loss of appetite, impaired gastric emptying time (GET) may be related to nutritional parameters and nutritional status of patients on renal replacement therapy (RRT). Patients on RRT are affected by several factors such as uremic toxins, the presence of dialysate in the peritoneal cavity, and the drugs used against renal allograft rejection. In this study, we investigated the gastric emptying time and its relationship with biochemical and nutritional parameters in patients on RRT: those on hemodialysis and peritoneal dialysis, and renal transplantation patients. Seventy-five patients, 44 on hemodialysis, 16 on peritoneal dialysis, and 15 renal transplant patients, were included in the study. They were examined for gastric emptying time using a radioisotopic method. The results were compared with the GET of healthy subjects. Each group of patients was evaluated in terms of hemoglobin, hematocrit, blood urea nitrogen (BUN), creatinine, blood glucose, total protein, albumin, serum lipids, parathyroid hormone (PTH) and body mass index and biceps and triceps skinfold. The mean GET of patients on RRT was significantly longer than the mean GET of healthy subjects (87.8 +/- 23.4 vs. 55 +/- 18 min, p0.05). In addition, time on replacement therapy inversely and blood glucose positively correlated with GET in renal transplant patients. In conclusion, GET was longer in patients on all three RRT modalities than in healthy subjects. GET was not significantly different in dialysis patients and renal transplant patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79634ae3e18e23c64735d5fda088730d https://pubmed.ncbi.nlm.nih.gov/15600252 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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