Clinical use of dexmedetomidine as premedicant in cats undergoing propofol–sevoflurane anaesthesia
| Autor: | Juliana P Figueiredo, G. M. Mendes, André Luis Selmi, Glenda Ramalho Barbudo-Selmi, B. T. Lins |
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| Rok vydání: | 2003 |
| Předmět: |
Methyl Ethers
Bradycardia medicine.medical_specialty Ovariectomy Premedication medicine.medical_treatment Blood Pressure Hysterectomy Sevoflurane Heart Rate medicine Animals Hypnotics and Sedatives Dexmedetomidine Infusions Intravenous Small Animals Propofol Saline CATS business.industry Respiration Surgery Blood pressure Anesthesia Anesthetics Inhalation Cats Female medicine.symptom business Anesthetics Intravenous medicine.drug |
| Zdroj: | Journal of Feline Medicine and Surgery. 5:265-270 |
| ISSN: | 1532-2750 1098-612X |
| DOI: | 10.1016/s1098-612x(03)00053-6 |
| Popis: | The purpose of this report was to evaluate the cardiorespiratory effects and efficacy of dexmedetomidine as a premedicant agent in cats undergoing ovariohysterectomy anaesthetized with propofol–sevoflurane. Cats were randomly divided into two groups of eight animals each. Dexmedetomidine (0.01 mg/kg) or 0.9% saline was administered intravenously (D and S, respectively). After 5 min, propofol was administered intravenously and anaesthesia was maintained with sevoflurane. Heart and respiratory rates, arterial blood pressure, oxygen saturation, rectal temperature and the amount of propofol needed for induction were measured. Premedication with dexmedetomidine reduced the requirement of propofol (6.7±3.8 mg/kg), but induced bradycardia, compared with the administration of saline (15.1±5.1 mg/kg). Recovery quality was significantly better in D but no significant difference in time to return of swallowing reflex was observed between groups (D=2.5±0.5 min;S=3.2±1.8 min). In conclusion, dexmedetomidine is a safe and effective agent for premedication in cats undergoing propofol–sevoflurane anaesthesia with minimal adverse effects. |
| Databáze: | OpenAIRE |
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