Hand Compartment Syndrome Due to N-acetylcysteine Extravasation

Autor:	Joby Thoppil, Benjamin Kessler, Payal Sud, Joshua Nogar, Adam Berman
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	business.industry medicine.medical_treatment digestive oral and skin physiology Case Report Compartment (chemistry) Emergency Nursing Extravasation Acetaminophen Fasciotomy Lesion Acetylcysteine Anesthesia Toxicity Emergency Medicine medicine medicine.symptom Antidote business medicine.drug
Zdroj:	Thoppil, Joby; Berman, Adam; Kessler, Benjamin; Sud, Payal; & Nogar, Joshua. (2017). Hand Compartment Syndrome Due to N-acetylcysteine Extravasation. Clinical Practice and Cases in Emergency Medicine, 1(4). doi: 10.5811/cpcem.2017.9.35152. Retrieved from: http://www.escholarship.org/uc/item/0b4897v3 Clinical Practice and Cases in Emergency Medicine
Popis:	N-acetylcysteine (NAC) is the antidote for acetaminophen (APAP)-induced hepatotoxicity. Both intravenous (IV) and oral (PO) NAC formulations are available with equal efficacy. Adverse events from either preparation are rare. We describe a hand compartment syndrome after extravasation of NAC requiring emergent fasciotomy during phase three of treatment for suspected APAP toxicity. Extravasation injuries leading to compartment syndrome are rare. It is unclear whether IV NAC induced a direct tissue-toxic insult, or functioned as a space-occupying lesion to cause a compartment syndrome. Compartment syndrome from extravasation of NAC is possible. In cases where IV access is difficult, PO NAC is an alternative.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795c051d677f3666930a08f925db16f7 http://www.escholarship.org/uc/item/0b4897v3 Zobrazit plný text záznamu