Hemodialysis patients with intradialytic rise in blood pressure display higher baseline aortic stiffness and negligible drop in augmentation index with dialysis
| Autor: | Panagiotis I. Georgianos, Dimitrios N. Stamatiadis, Pantelis Zebekakis, Pantelis Sarafidis, Vassilios Liakopoulos, Erasmia Sabani, Fani Mpoutsiouki, Elias V. Balaskas |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Nephrology medicine.medical_specialty Haemodynamic response Urology medicine.medical_treatment 030232 urology & nephrology Aorta Thoracic Blood Pressure Pulse Wave Analysis 030204 cardiovascular system & hematology 03 medical and health sciences Vascular Stiffness 0302 clinical medicine Renal Dialysis Internal medicine Humans Medicine Pulse wave velocity Greece business.industry Incidence Arteriosclerosis Middle Aged medicine.disease Surgery Blood pressure Cardiovascular Diseases Arterial stiffness Cardiology Kidney Failure Chronic Female Aortic stiffness Hemodialysis business Blood Flow Velocity Follow-Up Studies |
| Zdroj: | International Urology and Nephrology. 48:601-608 |
| ISSN: | 1573-2584 0301-1623 |
| DOI: | 10.1007/s11255-015-1205-8 |
| Popis: | In hemodialysis patients, the intradialytic rise in blood pressure (BP) is associated with increased mortality risk. However, the mechanisms of this adverse effect are not yet elucidated. This study examined whether intradialytic rise in BP is associated with increased arterial stiffness and wave reflections, which are powerful cardiovascular risk predictors in hemodialysis. The pattern of intradialytic hemodynamic response was evaluated in 70 prevalent hemodialysis patients, by measuring seated brachial BP before and after the mid-week dialysis session. All patients had pre- and post-dialysis determination of aortic pulse wave velocity (PWV) and heart rate-adjusted augmentation index [AIx(75)], as measures of arterial stiffness and wave reflections, with the Sphygmocor device. Intradialytic rise in brachial systolic BP (SBP) was evident in 17 patients, whereas intradialytic change in SBP (ΔSBP) of −10 to 0 mmHg was observed in 23 and ΔSBP greater than −10 mmHg in 30 patients. Participants with intradialytic SBP rise had significantly higher pre-dialysis aortic PWV (10.4 ± 1.6 vs 8.3 ± 1.9 vs 9.4 ± 2.4 m/s, P |
| Databáze: | OpenAIRE |
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