A US Multicenter Study of Safety and Efficacy of Fully Covered Self-Expandable Metallic Stents in Benign Extrahepatic Biliary Strictures
| Autor: | Vikesh K. Singh, Anthony N. Kalloo, Vivek Kumbhari, Jonathan M. Buscaglia, Srinadh Komanduri, Eun Ji Shin, Frederick Shieh, John Nasr, David L. Diehl, Wilson Sze, Sumit Kapoor, Mouen A. Khashab, Payal Saxena, Anne Marie Lennon |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Cholangitis Physiology medicine.medical_treatment Prosthesis Design Tertiary Care Centers Foreign-Body Migration Refractory Bile Ducts Extrahepatic Recurrence Risk Factors Self-expandable metallic stent Internal medicine medicine Humans Adverse effect Device Removal Aged Retrospective Studies Cholangiopancreatography Endoscopic Retrograde Cholestasis business.industry Gastroenterology Stent Middle Aged Hepatology equipment and supplies medicine.disease United States Prosthesis Failure Surgery Treatment Outcome surgical procedures operative Multicenter study Metals Drainage Pancreatitis Female Stents Radiology Complication business |
| Zdroj: | Digestive Diseases and Sciences. 60:3442-3448 |
| ISSN: | 1573-2568 0163-2116 |
| Popis: | Endoscopic therapy is considered first line for management of benign biliary strictures (BBSs). Placement of plastic stents has been effective but limited by their short-term patency and need for repeated procedures. Fully covered self-expandable metallic stents (FCSEMSs) offer longer-lasting biliary drainage without the need for frequent exchanges. The aim of this study was to assess the efficacy and safety of FCSEMS in patients with BBS. A retrospective review of all patients who underwent ERCP and FCSEMS placement at five tertiary referral US hospitals was performed. Stricture resolution and adverse events related to ERCP and/or stenting were recorded. A total of 123 patients underwent FCSEMS placement for BBS and 112 underwent a subsequent follow-up ERCP. The mean age was 62 years (±15.6), and 57 % were males. Stricture resolution occurred in 81 % of patients after a mean of 1.2 stenting procedures (mean stent dwell time 24.4 ± 2.3 weeks), with a mean follow-up of 18.5 months. Stricture recurrence occurred in 5 patients, and 3 patients required surgery for treatment of refractory strictures. Stent migration (9.7 %) was the most common complication, followed by stent occlusion (4.9 %), cholangitis (4.1 %), and pancreatitis (3.3 %). There was one case of stent fracture during removal, and one stent could not be removed. There was one death due to cholangitis. Majority of BBS can be successfully managed with 1–2 consecutive FCSEMS with stent dwell time of 6 months. |
| Databáze: | OpenAIRE |
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