Supplementary Figures from MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin

Autor: Karen L. MacKenzie, Jamie I. Fletcher, Giovanni Perini, Murray D. Norris, Preethi H. Gunaratne, Michelle Haber, Wendy B. London, Hilda A. Pickett, Georg von Jonquieres, Claudia L. Flemming, Amanda J. Russell, Jayne Murray, Chen Yang, Stefania Purgato, Cheng Fei Kong, Bing Liu, Michelle F. Maritz, Sieu L. Tran, Rosemary O'Brien
Rok vydání: 2023
DOI: 10.1158/0008-5472.22410275.v1
Popis: Supporting data; Supplementary Figure 1:Correlation analysis of DKC1 mRNA and dyskerin protein quantity in neuroblastoma cell lines Supplementary Figure 2:Correlation analysis of telomerase activity gene expression in neuroblastoma cells Supplementary Figure 3:Correlation analysis of TERT and MYC gene expression in neuroblastoma tumor samples Supplementary Figure 4:High DKC1 expression is a marker of poor prognosis in neuroblastoma Supplementary Figure 5:Analysis of TERT expression in neuroblastoma tumor samples Supplementary Figure 7: Upregulation of p21cip1 in NB69, but not SK-N-BE(2) cells following down regulation of dyskerin Supplementary Figure 8: Cell cycle and viability following downregulation of dyskerin
Databáze: OpenAIRE