Catalytic Deoxygenative Coupling of Aromatic Esters with Organophosphorus Compounds
| Autor: | Ryota Isshiki, Kei Muto, Junichiro Yamaguchi, Miki B. Kurosawa |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
inorganic chemicals
Hydrogen Ligand Sodium formate Phosphorus chemistry.chemical_element General Chemistry 010402 general chemistry 01 natural sciences Biochemistry Catalysis 0104 chemical sciences chemistry.chemical_compound Colloid and Surface Chemistry chemistry Reagent Organic chemistry Palladium |
| DOI: | 10.26434/chemrxiv.11973585.v1 |
| Popis: | We have developed a deoxygenative coupling of aromatic esters with diarylphosphine oxides/dialkyl phosphonates under palladium catalysis. In this reaction, aromatic esters can work as novel benzylation reagents to give the corresponding benzylic phosphorus compounds. The key of this reaction is the use of phenyl esters, an electron-rich diphosphine as a ligand, and sodium formate as a hydrogen source. Arylcarboxylic acids were also applicable in this reaction using (Boc)2O as an additive. Palladium/dcype worked as a bifunctional catalyst to activate the acyl C–O bond of the ester and to support the reduction with sodium formate. |
| Databáze: | OpenAIRE |
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