Transplantation of Graft Anti-Host Cytotoxic T Lymphocytes Along with Allogeneic Bone Marrow Skips Macrophage-Induced Graft-Versus-Host Disease

Autor:	Kazuhisa Uchiyama, Emi Yasuda, Yuro Shibayama, Takahiro Kubota, Nobuhiko Tanigawa, Ryotaro Yoshida, Michihiro Hayashi, Yoshinobu Hirose, Hidenori Yamana
Rok vydání:	2021
Předmět:	Male Immunology Graft vs Host Disease Graft vs Leukemia Effect chemical and pharmacologic phenomena Disease Interferon-gamma Mice Bone Marrow immune system diseases Cell Line Tumor Virology Animals Medicine Macrophage Cytotoxic T cell Autogenous bone Bone Marrow Transplantation Mice Inbred BALB C Mice Inbred C3H business.industry Effector Host (biology) Macrophages Hematopoietic Stem Cell Transplantation Cell Biology medicine.disease Mice Inbred C57BL Transplantation surgical procedures operative Graft-versus-host disease Mice Inbred DBA Mice Inbred CBA Interleukin-2 business T-Lymphocytes Cytotoxic
Zdroj:	Journal of Interferon & Cytokine Research. 41:310-318
ISSN:	1557-7465 1079-9907
DOI:	10.1089/jir.2021.0032
Popis:	Graft-versus-host disease (GVHD) is a physiological response of the graft to allogeneic hosts. However, the effector cells, affected organ(s), and cytokines in the GVHD remain controversially discussed, without having determined a particular cytotoxic activity of the graft against the host. After
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79488c50014fd96b0618c4f482e2e40a https://doi.org/10.1089/jir.2021.0032 Zobrazit plný text záznamu