Amoebae as Battlefields for Bacteria, Giant Viruses, and Virophages

Autor:	Isabelle Pagnier, Meriem Slimani, B. La Scola, Didier Raoult
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Mimivirus Virophages biology Bacteria Immunology Virophage Virulence biology.organism_classification Microbiology Virology Virus-Cell Interactions Insect Science parasitic diseases Viral Interference Mimiviridae Giant Virus Amoeba
Popis:	When amoebae are simultaneously infected with Acanthamoeba polyphaga Mimivirus (APM) and the strictly intracellular BABL1 bacterium, the latter is always lost after serial subculturing. We showed that the virophage Sputnik 1, by reducing APM fitness, preserved BABL1 growth in acute and chronic models. This capability of a virophage to modulate the virulence of mimiviruses highlights the competition that occurs between them during natural host infection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794798a879219f87c1bb7f32c9b05d1b https://europepmc.org/articles/PMC3624401/ Zobrazit plný text záznamu