Trends and patterns of analgesic prescribing in Malaysian public hospitals from 2010 to 2016: tramadol predominately used
Autor: | Kim Swan Ng, Nor Elina Alias, Nor Ilyani Mohamed Nazar, Felicia Loh Ye, Mary Suma Cardosa, Norny Syafinaz Ab Rahman, Wan Rohaidah Ahmad, Che Suraya Zin, Nurul Sahida Rani |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Ketoprofen
tramadol NSAIDs Analgesic 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Diclofenac medicine patterns 030212 general & internal medicine Journal of Pain Research Original Research trends of prescribing business.industry Malaysia opioids Dihydrocodeine Meloxicam Anesthesiology and Pain Medicine Opioid Anesthesia analgesics Tramadol business Oxycodone medicine.drug |
Zdroj: | Journal of Pain Research |
ISSN: | 1178-7090 |
Popis: | Che Suraya Zin,1 Nor Ilyani Nazar,1 Norny Syafinaz Rahman,1 Nor Elina Alias,1 Wan Rohaidah Ahmad,2 Nurul Sahida Rani,3 Mary Suma Cardosa,4 Kim Swan Ng,4 Felicia Loh Ye5 1Department of Pharmacy Practice, Kulliyah of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia; 2Department of Anaesthesiology and Intensive Care, Hospital Sultanah Nur Zahirah, Kuala Terengganu, Malaysia; 3Department of Pharmacy, Hospital Sultanah Nur Zahirah, Kuala Terengganu, Malaysia; 4Department of Anaesthesiology and Intensive Care, Hospital Selayang, Batu Caves, Malaysia; 5Department of Pharmacy, Hospital Selayang, Batu Caves, Malaysia Purpose: To examine the trends of analgesic prescribing at public tertiary hospital outpatient settings and explore the patterns of their utilization in nonsteroidal anti-inflammatory drugs (NSAIDs), tramadol, and opioid patients. Patients and methods: This cross-sectional study was conducted from 2010 to 2016 using the prescription databases of two tertiary hospitals in Malaysia. Prescriptions for nine NSAIDs (ketoprofen, diclofenac, celecoxib, etoricoxib, ibuprofen, indomethacin, meloxicam, mefenamic acid, and naproxen), tramadol, and five other opioids (morphine, fentanyl, oxycodone, dihydrocodeine, and buprenorphine) were included in this study. Annual number of patients and prescriptions were measured in repeat cross-sectional estimates. Descriptive statistics and linear trend analysis were performed using Stata version 13. Results: A total of 192,747 analgesic prescriptions of the nine NSAIDs, tramadol, and five other opioids were given for 97,227 patients (51.8% NSAIDs patients, 46.6% tramadol patients, and 1.7% opioid patients) from 2010 to 2016. Tramadol (37.9%, n=72,999) was the most frequently prescribed analgesic, followed by ketoprofen (17.5%, n=33,793), diclofenac (16.2%, n=31,180), celecoxib (12.2%, n=23,487), and other NSAIDs ( |
Databáze: | OpenAIRE |
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