Intraarticular and serum vancomycin concentration added to acrylic cement
| Autor: | Jadwiga Majchrzak, Marek Wiszniowski, Ireneusz Babiak, Mirosław Grzeszczyk, Iwona Korzeniewska-Rybicka |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Drug
medicine.medical_specialty medicine.drug_class medicine.medical_treatment media_common.quotation_subject Antibiotics vancomycin two-stage revision end-stage kidney disease medicine In patient media_common Cement infected knee prosthesis hemodialysis business.industry General Medicine high-flux hemodialysis biochemical phenomena metabolism and nutrition Orthopaedic implant Surgery antibiotic loaded acrylic cement spacer Toxicity Vancomycin Medicine Hemodialysis business medicine.drug |
| Zdroj: | Open Medicine, Vol 9, Iss 3, Pp 455-460 (2014) |
| ISSN: | 2391-5463 |
| Popis: | Background Vancomycin is the antibiotic of choice in therapy of orthopaedic implant infections caused by methicillin-resistant bacteria but its use poses a risk of toxicity, especially in patients with renal insufficiency. Addition of vancomycin to acrylic cement may cause systemic exposition to this drug eluting from cement to serum, which may require high-flux hemodialysis. |
| Databáze: | OpenAIRE |
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