Prevalence and Outcome of Congenital Left Ventricular Aneurysms and Diverticula in an Adult Population
| Autor: | Maria A. Secknus, Bernward Lauer, Johann Christoph Geller, Hubertus von Korn, Marc-Alexander Ohlow |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Cardiac Catheterization medicine.medical_specialty Heart Ventricles medicine.medical_treatment Adult population Catheter ablation digestive system Risk Factors Germany Internal medicine Prevalence medicine Humans Pharmacology (medical) cardiovascular diseases Heart Aneurysm Diverticulum (mollusc) Survival rate Aged Retrospective Studies Cardiac catheterization Aged 80 and over business.industry Follow up studies Retrospective cohort study Middle Aged medicine.disease digestive system diseases Defibrillators Implantable Radiography Survival Rate Diverticulum Treatment Outcome Catheter Ablation cardiovascular system Cardiology Female Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | Cardiology. 112:287-293 |
| ISSN: | 1421-9751 0008-6312 |
| DOI: | 10.1159/000159122 |
| Popis: | Objectives: We sought to investigate the prevalence and clinical outcome of congenital left ventricular aneurysms (LVAs) and diverticula (LVD) in a large adult population. Methods: We retrospectively studied the left ventricular angiograms of 12,271 consecutive patients undergoing cardiac catheterization at our institution and analyzed the medical records of the patients. Results: The overall prevalence of LVA/LVD was 0.76% (94 patients): there were 42 patients with LVA (0.34%) and 52 patients with LVD (0.42%). Men were more likely to have LVA (62 vs. 38%), and women were more likely to have LVD (75 vs. 25%; p = 0.001 for both). The mean time of follow-up was 56 ± 6 months and was focused on clinical events, rehospitalization and survival. Mortality was 6% with no cardiac death. Patients with LVD were significantly more likely to have embolic events (p = 0.04). Patients with LVA and LVD were more likely to have rhythm disturbances compared with controls (p = 0.01 for both). Incidence of syncope was not different in both groups (p = 0.4 and 0.12, respectively). There was no reported incidence of rupture. Conclusion: This large single-center study suggests that the prevalence of LVA/LVD in adults is up to 20-fold higher than previously reported. One third of the affected patients in our series had nonfatal cardiovascular events during follow-up, with a predominance of embolic events in the LVD group. |
| Databáze: | OpenAIRE |
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