Ethnic differences in inflammatory bowel disease: results from the UNited Kingdom IncepTion Epidemiology (UNITE) study
| Autor: | Samia Sakuma, Matthew J Brookes, Tariq Iqbal, Edward Fogden, Rachel Cooney, Ravi Misra, Naveen Sharma, Jimmy K. Limdi, Pia Munkholm, Johan Burisch, Sanjeev S. Pattni, Naila Arebi |
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| Přispěvatelé: | St Mark's Foundation |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Databases Factual Epidemiology Ethnic group Prevalence Observational Study Inflammatory bowel disease White People Colitis Ulcerative/ethnology 03 medical and health sciences 0302 clinical medicine European Continental Ancestry Group/statistics & numerical data Asian People Catchment Area Health Crohn Disease medicine Ethnicity Humans Prospective Studies Catchment Area Health/statistics & numerical data Crohn's disease Gastroenterology & Hepatology United Kingdom/epidemiology business.industry Incidence (epidemiology) Incidence Gastroenterology 1103 Clinical Sciences General Medicine Crohn Disease/ethnology Middle Aged Databases Factual/statistics & numerical data medicine.disease Ulcerative colitis INCEPTION COHORT United Kingdom Phenotype Asian Continental Ancestry Group/statistics & numerical data 030220 oncology & carcinogenesis Family medicine 030211 gastroenterology & hepatology Colitis Ulcerative Female business |
| Zdroj: | World Journal of Gastroenterology Misra, R, Limdi, J, Cooney, R, Sakuma, S, Brookes, M, Fogden, E, Pattni, S, Sharma, N, Iqbal, T, Munkholm, P, Burisch, J & Arebi, N 2019, ' Ethnic differences in inflammatory bowel disease : Results from the United Kingdom inception cohort epidemiology study ', World Journal of Gastroenterology, vol. 25, no. 40, pp. 6145-6157 . https://doi.org/10.3748/wjg.v25.i40.6145 |
| Popis: | Aim To describe the incidence and phenotype of IBD and distribution within ethnic groups. Methods Adult patients (>16 years) with newly diagnosed IBD (fulfilling Copenhagen diagnostic criteria) were prospectively recruited over one year in 5 urban catchment areas with high South Asian population. Patient demographics, ethnic codes, disease phenotype (Montreal classification), disease activity and treatment within 3 months of diagnosis were recorded onto the Epicom database. Results Across a population of 2,271,406 adults, 339 adult patients were diagnosed with IBD over one year: 218 with UC (64.3%), 115 with CD (33.9%) and 6 with IBDU (1.8%). The crude incidence of IBD, UC and CD was 17.0/100,000, 11.3/100,000 and 5.3/100,000 respectively. The age adjusted incidence of IBD and UC were significantly higher in the Indian group (25.2.100,000 and 20.5/100,000) compared to White European (14.9/100,000, p=0.009 and 8.2/100,000, p |
| Databáze: | OpenAIRE |
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