Novel Basic Science Insights to Improve the Management of Heart Failure: Review of the Working Group on Cellular and Molecular Biology of the Heart of the Italian Society of Cardiology

Autor: Roberta Paolillo, Edoardo Bertero, Gabriele G. Schiattarella, Margherita Torchio, Daniele Rodolico, Sebastiano Sciarretta, Cristina Basso, Pietro Ameri, Maurizio Forte, Vittoria Di Mauro, Daniele Torella, Lia Crotti, Daniele Catalucci, Cristina Chimenti, Cinzia Perrino, Ciro Indolfi
Přispěvatelé: Ameri, P, Schiattarella, G, Crotti, L, Torchio, M, Bertero, E, Rodolico, D, Forte, M, Di Mauro, V, Paolillo, R, Chimenti, C, Torella, D, Catalucci, D, Sciarretta, S, Basso, C, Indolfi, C, Perrino, C, Ameri, P., Schiattarella, G. G., Crotti, L., Torchio, M., Bertero, E., Rodolico, D., Forte, M., Di Mauro, V., Paolillo, R., Chimenti, C., Torella, D., Catalucci, D., Sciarretta, S., Basso, C., Indolfi, C., Perrino, C.
Rok vydání: 2020
Předmět:
0301 basic medicine
Basic science
Review
030204 cardiovascular system & hematology
Translational Research
Biomedical
lcsh:Chemistry
Drug Delivery Systems
0302 clinical medicine
Mechanisms
Myocytes
Cardiac
lcsh:QH301-705.5
Societies
Medical
Spectroscopy
High potential
Microbiota
Translational
Disease Management
General Medicine
Prognosis
3. Good health
Computer Science Applications
Italy
medicine.medical_specialty
Management of heart failure
mechanism
Heart failure
Translational research
Catalysis
Prognostic stratification
Inorganic Chemistry
03 medical and health sciences
Basic
Research
Autophagy
medicine
Animals
Humans
Genetic Predisposition to Disease
ddc:610
Physical and Theoretical Chemistry
Intensive care medicine
Molecular Biology
Inflammation
business.industry
Organic Chemistry
MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE
030104 developmental biology
lcsh:Biology (General)
lcsh:QD1-999
Cardiovascular and Metabolic Diseases
business
Zdroj: International Journal of Molecular Sciences, Vol 21, Iss 4, p 1192 (2020)
International Journal of Molecular Sciences
ISSN: 1422-0067
Popis: Despite important advances in diagnosis and treatment, heart failure (HF) remains a syndrome with substantial morbidity and dismal prognosis. Although implementation and optimization of existing technologies and drugs may lead to better management of HF, new or alternative strategies are desirable. In this regard, basic science is expected to give fundamental inputs, by expanding the knowledge of the pathways underlying HF development and progression, identifying approaches that may improve HF detection and prognostic stratification, and finding novel treatments. Here, we discuss recent basic science insights that encompass major areas of translational research in HF and have high potential clinical impact.
Databáze: OpenAIRE
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