Novel Basic Science Insights to Improve the Management of Heart Failure: Review of the Working Group on Cellular and Molecular Biology of the Heart of the Italian Society of Cardiology
Autor: | Roberta Paolillo, Edoardo Bertero, Gabriele G. Schiattarella, Margherita Torchio, Daniele Rodolico, Sebastiano Sciarretta, Cristina Basso, Pietro Ameri, Maurizio Forte, Vittoria Di Mauro, Daniele Torella, Lia Crotti, Daniele Catalucci, Cristina Chimenti, Cinzia Perrino, Ciro Indolfi |
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Přispěvatelé: | Ameri, P, Schiattarella, G, Crotti, L, Torchio, M, Bertero, E, Rodolico, D, Forte, M, Di Mauro, V, Paolillo, R, Chimenti, C, Torella, D, Catalucci, D, Sciarretta, S, Basso, C, Indolfi, C, Perrino, C, Ameri, P., Schiattarella, G. G., Crotti, L., Torchio, M., Bertero, E., Rodolico, D., Forte, M., Di Mauro, V., Paolillo, R., Chimenti, C., Torella, D., Catalucci, D., Sciarretta, S., Basso, C., Indolfi, C., Perrino, C. |
Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Basic science Review 030204 cardiovascular system & hematology Translational Research Biomedical lcsh:Chemistry Drug Delivery Systems 0302 clinical medicine Mechanisms Myocytes Cardiac lcsh:QH301-705.5 Societies Medical Spectroscopy High potential Microbiota Translational Disease Management General Medicine Prognosis 3. Good health Computer Science Applications Italy medicine.medical_specialty Management of heart failure mechanism Heart failure Translational research Catalysis Prognostic stratification Inorganic Chemistry 03 medical and health sciences Basic Research Autophagy medicine Animals Humans Genetic Predisposition to Disease ddc:610 Physical and Theoretical Chemistry Intensive care medicine Molecular Biology Inflammation business.industry Organic Chemistry MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE 030104 developmental biology lcsh:Biology (General) lcsh:QD1-999 Cardiovascular and Metabolic Diseases business |
Zdroj: | International Journal of Molecular Sciences, Vol 21, Iss 4, p 1192 (2020) International Journal of Molecular Sciences |
ISSN: | 1422-0067 |
Popis: | Despite important advances in diagnosis and treatment, heart failure (HF) remains a syndrome with substantial morbidity and dismal prognosis. Although implementation and optimization of existing technologies and drugs may lead to better management of HF, new or alternative strategies are desirable. In this regard, basic science is expected to give fundamental inputs, by expanding the knowledge of the pathways underlying HF development and progression, identifying approaches that may improve HF detection and prognostic stratification, and finding novel treatments. Here, we discuss recent basic science insights that encompass major areas of translational research in HF and have high potential clinical impact. |
Databáze: | OpenAIRE |
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