ALPHA-INTERFERON THERAPY FOR ESSENTIAL THROMBOCYTHAEMIA
| Autor: | A. V. Hoffbrand, I. R. Grant, F.J Giles, S.C Davies, A.G Gray, Kwee Yong, Ah Goldstone, M Brozovic, Atul Mehta, J.D.M. Richards, S. J. Machin, C. R. J. Singer, S Venutas, M.J.G Thomas |
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| Rok vydání: | 1988 |
| Předmět: |
Adult
Male medicine.medical_specialty Alternative therapy medicine.medical_treatment Alpha interferon Gastroenterology law.invention Hemoglobins Leukocyte Count law Internal medicine medicine Humans Platelet Interferon alfa Aged Chemotherapy Platelet Count business.industry General Medicine Middle Aged Interferon Type I Immunology Recombinant DNA Female business Previously treated Interferon type I Thrombocythemia Essential medicine.drug |
| Zdroj: | The Lancet. 332:70-72 |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/s0140-6736(88)90005-0 |
| Popis: | 18 patients with symptomatic essential thrombocythaemia were treated with recombinant alpha interferon (2a or 2b). Subcutaneous dosage regimens, which were well-tolerated, selectively lowered the platelet count and relieved symptoms in all patients, whether previously treated or untreated. Recombinant alpha-interferon may offer a non-leukaemogenic alternative therapy for these patients. |
| Databáze: | OpenAIRE |
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