A case of polyarteritis nodosa complicated by left central retinal artery occlusion, ischemic optic neuropathy, and retinal vasculitis
| Autor: | F. Zeinhom, S. Basaffar, Yasser Ragab, Yasser Emad, Tamer A. Gheita |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Retinal Vasculitis medicine.medical_specialty medicine.diagnostic_test Mononeuritis Multiplex Retinal vasculitis Polyarteritis nodosa business.industry Retinal Artery Occlusion General Medicine Ischemic optic neuropathy medicine.disease Surgery Polyarteritis Nodosa Optic neuropathy Rheumatology Angiography Occlusion medicine Central retinal artery occlusion Humans Female Optic Neuropathy Ischemic business |
| Zdroj: | Clinical rheumatology. 26(5) |
| ISSN: | 0770-3198 |
| Popis: | A 23-year-old single female patient developed constitutional manifestations in the form of fever, weight loss, anorexia, malaise, fatigue, and generalized aches in January 1995, 2 weeks after an attack of German measles. This was followed by painful, reddish, macular skin lesions over both legs which healed by dark pigmentation (leucocytoclastic vasculitis), mononeuritis multiplex, and Raynaud’s phenomena of both hands and feet. Angiography of lower limbs was done to visualize the arterial tree of both lower limbs and revealed typical beading of distal arterial branches, a diagnosis compatible with polyarteritis nodosa (PAN). At that time, the patient received prednisone (45 mg/day) and azatioprin (100 mg/day) and responded well to treatment. In a second presentation in June 2005, the patient developed sudden attack of loss of vision in her left eye. Ophthalmological examination of the patient revealed evidence of left central retinal artery occlusion, ischemic optic neuropathy. The patient received methyl prednisolone, 1 g IV infusion, daily infusion for three consecutive days followed by oral prednisolone, 30 mg/day. The patient received pulse cyclophosphamide IV infusion (0.6 g/m2) on the fourth day. One week after receiving therapy, the patient progressed from having light perception to counting of fingers from a distance of 1 m. |
| Databáze: | OpenAIRE |
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