Tooth Loss Increases the Risk of Diminished Cognitive Function: A Systematic Review and Meta-analysis
Autor: | Daiane Cerutti-Kopplin, Jocelyne S. Feine, Dalva Maria Pereira Padilha, M. Ahmadi, R. F. B. de Souza, Linda Booij, Pierre H. Rompré, Elham Emami |
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Rok vydání: | 2019 |
Předmět: |
Gerontology
medicine.medical_specialty Dentition business.industry Hazard ratio 030206 dentistry Cochrane Library medicine.disease 03 medical and health sciences 0302 clinical medicine Internal medicine Meta-analysis medicine Tooth loss Dementia Cognitive decline medicine.symptom business General Dentistry 030217 neurology & neurosurgery Cohort study |
Zdroj: | JDR clinical and translational research. 1(1) |
ISSN: | 2380-0852 |
Popis: | Emerging evidence suggests that oral health is associated with cognitive function. This review aims to systematically assess this association in adult populations via prospective cohort study designs. Eligible study reports were identified by searching the MEDLINE (via Ovoid), EMBASE, PsycoINFO, and Cochrane Library databases. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated with a random effects model. From 1,251 identified articles, 10 were included in the systematic review and 8 in the meta-analysis. Random effects analysis showed, with statistically low heterogeneity, that individuals with suboptimal dentition ( Knowledge Transfer Statement: Based on the published literature, the results of this study show that the risk for cognitive impairment and dementia increases with loss of teeth. This information adds to the evidence showing links between oral and general health and suggests that oral health strategies aimed to preserve teeth may be important in reducing risk of systemic disease. |
Databáze: | OpenAIRE |
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