Tooth Loss Increases the Risk of Diminished Cognitive Function: A Systematic Review and Meta-analysis

Autor: Daiane Cerutti-Kopplin, Jocelyne S. Feine, Dalva Maria Pereira Padilha, M. Ahmadi, R. F. B. de Souza, Linda Booij, Pierre H. Rompré, Elham Emami
Rok vydání: 2019
Předmět:
Zdroj: JDR clinical and translational research. 1(1)
ISSN: 2380-0852
Popis: Emerging evidence suggests that oral health is associated with cognitive function. This review aims to systematically assess this association in adult populations via prospective cohort study designs. Eligible study reports were identified by searching the MEDLINE (via Ovoid), EMBASE, PsycoINFO, and Cochrane Library databases. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated with a random effects model. From 1,251 identified articles, 10 were included in the systematic review and 8 in the meta-analysis. Random effects analysis showed, with statistically low heterogeneity, that individuals with suboptimal dentition ( Knowledge Transfer Statement: Based on the published literature, the results of this study show that the risk for cognitive impairment and dementia increases with loss of teeth. This information adds to the evidence showing links between oral and general health and suggests that oral health strategies aimed to preserve teeth may be important in reducing risk of systemic disease.
Databáze: OpenAIRE