Determination of flubendiamide in honey at trace levels by using solid phase extraction and liquid chromatography coupled to quadrupole time-of-flight mass spectrometry
| Autor: | Ana M. Ares, José L. Bernal, José Bernal, Laura Toribio, María J. Nozal, Silvia Valverde |
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| Rok vydání: | 2017 |
| Předmět: |
Analyte
Sorbent Analytical chemistry 010501 environmental sciences Mass spectrometry 01 natural sciences Mass Spectrometry Analytical Chemistry chemistry.chemical_compound Tandem Mass Spectrometry Phase (matter) Sulfones Solid phase extraction Acetonitrile Chromatography High Pressure Liquid 0105 earth and related environmental sciences Detection limit Chromatography Chemistry Solid Phase Extraction 010401 analytical chemistry Honey General Medicine 0104 chemical sciences Benzamides Quantitative analysis (chemistry) Chromatography Liquid Food Science |
| Zdroj: | Food Chemistry. 232:169-176 |
| ISSN: | 0308-8146 |
| Popis: | In this study, a new method has been developed to determine flubendiamide in honey using liquid chromatography coupled to a selective mass spectrometry detector (quadrupole-time-of-flight). An efficient sample treatment involving a solid phase extraction with a C18 sorbent was proposed (average analyte recoveries were between 94 and 104%). Chromatographic analysis (9 min) was performed on a C18 column (Gemini C18, 50 × 2.0 mm, 3 µm, 110 A). The mobile phase consisted of water and acetonitrile, with a flow rate of 0.5 mL/min in gradient elution mode. The method was fully validated in terms of selectivity, limits of detection and quantification, matrix effect, linearity, trueness and precision. Low limits of detection and quantification were obtained, ranging from 0.1 to 0.2 µg/kg and 0.4 to 0.6 µg/kg, respectively. The method was applied to analyze flubendiamide in honey from different botanic origins (multifloral, rosemary and heather). |
| Databáze: | OpenAIRE |
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