Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation
| Autor: | M Y Mohd Naim, O Syazarina Sharis, Wan Yahya Nafisah, K K Shahedah, Ching Soong Khoo, Chen Fei Ng, W Z Wan Asyraf, Z Rozman, I Noor Ashikin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Perfusion scanning Education 03 medical and health sciences 0302 clinical medicine Fibrinolytic Agents Modified Rankin Scale Internal medicine Occlusion medicine Humans atrial fibrillation 030212 general & internal medicine cardiovascular diseases Stroke lcsh:R5-920 Intention-to-treat analysis business.industry Penumbra wake-up stroke Atrial fibrillation General Medicine Thrombolysis r-tPA medicine.disease Recombinant Proteins Tissue Plasminogen Activator Reperfusion Cardiology Administration Intravenous Female computed tomography perfusion business lcsh:Medicine (General) 030217 neurology & neurosurgery |
| Zdroj: | The Journal of the Royal College of Physicians of Edinburgh, Vol 48, Iss 3, Pp 239-241 (2018) |
| ISSN: | 2042-8189 1478-2715 |
| Popis: | A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale (NIHSS) score was 17. An emergency CT perfusion showed right M1 segment occlusion with more than 50% penumbra. She was given recombinant tissue plasminogen activator (r-tPA) at 9 h from TLSW. An immediate diagnostic angiogram with intention to treat, owing to the presence of large vessel occlusion, showed complete reperfusion after intravenous r-tPA. She was discharged with NIHSS of 2, and at 3-month follow up her Modified Rankin Scale was 0. We demonstrated a successful reperfusion and excellent clinical recovery with intravenous thrombolysis in a patient who presented with a wake-up stroke with underlying valvular atrial fibrillation despite evidence of large vessel occlusion. © 2018, Royal College of Physicians of Edinburgh. All rights reserved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|