Mixed Germ Cell Tumour in an Infertile Male Having Unilateral Cryptorchidism: A Rare Case Report
| Autor: | Rupesh Nagori, Navneet Kaur, Gunjeet Singh Sandhu, Anand Singla |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty endocrine system Clinical Biochemistry cryptorchid testis lcsh:Medicine Surgery Section Unilateral cryptorchidism Embryonal carcinoma 03 medical and health sciences 0302 clinical medicine Scrotum medicine Yolk sac Gynecology business.industry azoospermia lcsh:R yolk sac tumour General Medicine Seminoma medicine.disease Left Testis 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis Teratoma business infertility malignant mixed germ cell tumour Germ cell |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 10, Iss 2, Pp PD17-PD18 (2016) |
| Popis: | Mixed germ cell tumours with multiple components occur more frequently than the pure varieties of germ cell tumours. Embryonal carcinoma and teratoma together form the most common components of the mixed germ cell tumour but the yolk sac tumour is usually seen as a minor component in patients presenting with mixed germ cell tumour. We report a rare case of 27-year-old Hepatitis C positive male presenting with pain in left lower abdomen with associated history of same sided undescended testis and infertility. Right sided testis lying in scrotal sac appeared normal on ultrasonography but patient was azoospermic. He had raised levels of serum markers, alpha feto protein and beta HCG. Examination showed a large mass in left lower abdomen involving the sigmoid colon with the absence of left testis in left scrotum which was confirmed on CT scan. Excision of the mass was done and histopathology examination revealed it as a malignant mixed germ cell tumour composed predominantly of a yolk sac tumour, with minor component as seminoma and embryonal carcinoma in an undescended testis. Following this, the level of serum markers came down. The patient is now undergoing adjuvant chemotherapy and is doing well. |
| Databáze: | OpenAIRE |
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