Photo-induced graft-versus-host disease
| Autor: | Laurence Lamant, Cécile Borel, Céline Pauwels, Carle Paul, Cristina Bulai Livideanu, Marie-Claude Marguery, Chloé Alberto, Anne Huynh, M. Thomas, Juliette Mazereeuw Hautier, J.M. Hardy, Emilie Tournier, Pol André Apoil |
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| Přispěvatelé: | CHU Toulouse [Toulouse], Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), Unité différenciation épidermique et auto-immunité rhumatoïde (UDEAR), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM), Pistre, Karine |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Male MESH: Hematopoietic Stem Cell Transplantation [SDV]Life Sciences [q-bio] MESH: Allografts Photodermatosis Graft vs Host Disease Disease 030207 dermatology & venereal diseases MESH: Skin Diseases* / etiology 0302 clinical medicine immune system diseases Immunology and Allergy MESH: Graft vs Host Disease* / etiology photodermatosis MESH: Middle Aged integumentary system Hematopoietic Stem Cell Transplantation General Medicine Middle Aged Allografts 3. Good health [SDV] Life Sciences [q-bio] Haematopoiesis MESH: Ultraviolet Rays / adverse effects Ultraviolet B radiation surgical procedures operative Phototesting Adult ultraviolet radiation Ultraviolet Rays Immunology chemical and pharmacologic phenomena Dermatology Skin Diseases 03 medical and health sciences medicine Humans Radiology Nuclear Medicine and imaging overlap chronic GVH disease MESH: Humans business.industry MESH: Chronic Disease MESH: Adult medicine.disease MESH: Male Transplantation MESH: Skin Diseases* / pathology 030104 developmental biology Graft-versus-host disease Chronic Disease Chronic gvhd business ultraviolet B MESH: Graft vs Host Disease* / pathology |
| Zdroj: | Photodermatology, Photoimmunology & Photomedicine Photodermatology, Photoimmunology & Photomedicine, Wiley, 2016, 32 (5-6), pp.291-295. ⟨10.1111/phpp.12273⟩ Photodermatology, Photoimmunology & Photomedicine, 2016, 32 (5-6), pp.291-295. ⟨10.1111/phpp.12273⟩ |
| ISSN: | 1600-0781 0905-4383 |
| DOI: | 10.1111/phpp.12273⟩ |
| Popis: | International audience; Overlap chronic graft-versus-host disease (GVHD) associates both features of acute and chronic GVHD. Trigger factors for chronic GVHD are unclear. We describe two patients who received allogenic haematopoietic stem-cell transplantation, and who later developed overlap chronic GVHD after sun exposure. Available data from in vivo investigations suggest ultraviolet B radiation (UVB) has a beneficial effect on acute and chronic GVHD. The role of sun irradiation as a trigger for isomorphic cutaneous GVHD has been rarely reported in the literature. Herein, we demonstrate for the first time, using repetitive broadband phototesting, that UVB triggers chronic GVHD. |
| Databáze: | OpenAIRE |
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