Microwave-Assisted Solvent-Free Synthesis of Substituted 2-Quinolones

Autor: Ya-Wei Dong, Shu-Jiang Tu, Guan-Wu Wang, Cheng-Sheng Jia
Rok vydání: 2007
Předmět:
Zdroj: ChemInform. 38
ISSN: 1522-2667
0931-7597
DOI: 10.1002/chin.200721131
Popis: A rapid and efficient method for the preparation of a variety of substituted 2-quinolones has been developed through the reactions of o-aminoarylketones with ester compounds containing a reactive α-methylene moiety in the presence of a catalytic amount of cerium chloride heptahydrate under solvent-free conditions in high yields. The rate and yield of the reaction are considerably improved by employing microwave irradiation.
Databáze: OpenAIRE