Changes in lipid composition and desaturase activities of duodenal mucosa induced by dietary fat
| Autor: | M. D. Giron, F.J. Mataix, María Dolores Suárez |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Fatty Acid Desaturases
Male food.ingredient Duodenum Linoleic acid Palmitic Acid Biophysics Phospholipid Palmitic Acids Biology Biochemistry Linoleic Acid Palmitic acid chemistry.chemical_compound Dogs Endocrinology food Intestinal mucosa Animals Plant Oils Sunflower Oil Food science Intestinal Mucosa Olive Oil Phospholipids chemistry.chemical_classification Cholesterol Sunflower oil Fatty Acids Lipid Metabolism Dietary Fats Linoleic Acids chemistry Microsome Female Polyunsaturated fatty acid |
| Zdroj: | Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1045:69-73 |
| ISSN: | 0005-2760 |
| DOI: | 10.1016/0005-2760(90)90204-b |
| Popis: | In the present work we have studied the effects of feeding either olive or sunflower oil on lipid composition and desaturase activities of duodenal mucosa microsomes. Duodenal microsomes prepared from dogs fed the sunflower oil diet showed higher percentages of saturated, of linoleic and of n - 3 polyunsaturated fatty acids as well as lower levels of oleic, dihomo-gamma-linolenic and arachidonic acids in phosphatidylcholine and phosphatidylethanolamine than those prepared from animals fed the olive oil diet. In sphingomyelin, the dietary supplementation did not produce significant differences between the two groups. The cholesterol/phospholipid molar ratio was higher in the sunflower oil group than in the olive oil group. The in vitro delta 9-desaturase activity was higher in microsomes from the olive oil dogs. The delta 6-desaturase activity was similar in microsomes from the two groups and lower than that found for delta 9-desaturase activity. Desaturase activities were higher in duodenal microsomes than those previously found for liver microsomes. |
| Databáze: | OpenAIRE |
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